蜘蛛毒性咬伤的临床后果。
Clinical consequences of toxic envenomation by spiders.
作者信息
Vetter Richard S
机构信息
Department of Entomology, University of California, Riverside, CA 92521 USA.
出版信息
Toxicon. 2018 Sep 15;152:65-70. doi: 10.1016/j.toxicon.2018.07.021. Epub 2018 Jul 24.
Spider venom is being researched for its potential use in applications such as insecticides, to better understand the dynamics of neuronal ion channel physiology and as potential remedies to counter antibiotic resistant bacteria. However, spider venom is more widely known for its ability to cause deleterious reactions after toxic envenomations in humans. In this short review, the "dark" side of spider venoms is presented to provide a counterbalance to the investigations of the positive potential that venoms can or might improve our world or its understanding. The goal was to present a short primer on species having clinical consequences in humans rather than be an exhaustive review of all spiders of medical importance.
蜘蛛毒液正因其在杀虫剂等应用中的潜在用途而受到研究，以便更好地理解神经元离子通道生理学的动态变化，并作为对抗抗生素耐药细菌的潜在疗法。然而，蜘蛛毒液更广为人知的是其在人类中毒性咬伤后引发有害反应的能力。在这篇简短的综述中，展示了蜘蛛毒液的“阴暗”面，以平衡对毒液积极潜力的研究，这些潜力可能或有望改善我们的世界或增进我们对它的理解。目标是提供一份关于对人类有临床影响的蜘蛛种类的简短入门介绍，而不是对所有具有医学重要性的蜘蛛进行详尽的综述。
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