Phylactou Maria, Matarazzo Francesco, Jones Emma
162 City Road, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
BMJ Case Rep. 2018 Jul 26;2018:bcr-2018-225920. doi: 10.1136/bcr-2018-225920.
We describe a case of indapamide-induced bilateral choroidal effusion, first time reported in pseudophakic patient, associated with no change in visual acuity and stable refraction.A 70-year-old man was referred for ophthalmic assessment, with binasal visual field defect for 2 days. He had been started on treatment with indapamide 3 weeks earlier. His ophthalmic history included bilateral cataract surgery and intraocular lens implant. Fundal examination revealed bilateral choroidal effusions; B-scan ultrasonography was used to measure the extent of the choroidal detachment and the anterior chamber depth. Discontinuation of indapamide resulted in spontaneous resolution of choroidal effusion after 3 days. Our case is the first in the literature that describes bilateral choroidal effusion induced by indapamide in a pseudophakic patient. The lack of myopic shift likely resulted in a later presentation, enhancing the theory that lens thickening and/or accommodative spasm may play a crucial role in pathophysiology.
我们描述了一例因吲达帕胺引起的双侧脉络膜积液病例,这是首次在人工晶状体植入患者中报道,该病例视力无变化且屈光稳定。一名70岁男性因双眼鼻侧视野缺损2天前来眼科评估。他在3周前开始服用吲达帕胺进行治疗。他的眼科病史包括双侧白内障手术和人工晶状体植入。眼底检查发现双侧脉络膜积液;使用B超超声检查来测量脉络膜脱离的程度和前房深度。停用吲达帕胺后,脉络膜积液在3天后自行消退。我们的病例是文献中首例描述人工晶状体植入患者因吲达帕胺引起双侧脉络膜积液的病例。缺乏近视性移位可能导致了较晚的临床表现,这进一步支持了晶状体增厚和/或调节痉挛可能在病理生理学中起关键作用的理论。