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DNA methylation haplotypes as cancer markers.

作者信息

Seoighe Cathal, Tosh Nick J, Greally John M

机构信息

School of Mathematics, Statistics and Applied Mathematics, National University of Ireland Galway, Galway, Ireland.

School of Humanities, National University of Ireland Galway, Galway, Ireland.

出版信息

Nat Genet. 2018 Aug;50(8):1062-1063. doi: 10.1038/s41588-018-0185-x.

DOI:10.1038/s41588-018-0185-x
PMID:30054597
Abstract
摘要

相似文献

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DNA methylation haplotypes as cancer markers.作为癌症标志物的DNA甲基化单倍型
Nat Genet. 2018 Aug;50(8):1062-1063. doi: 10.1038/s41588-018-0185-x.
2
Reply to 'DNA methylation haplotypes as cancer markers'.对“作为癌症标志物的DNA甲基化单倍型”的回复
Nat Genet. 2018 Aug;50(8):1063-1066. doi: 10.1038/s41588-018-0186-9.
3
General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells.正常细胞中通用转录因子与 CpG 岛的结合与癌细胞中从头 DNA 甲基化的抗性相关。
Cancer Res. 2010 Feb 15;70(4):1398-407. doi: 10.1158/0008-5472.CAN-09-3406. Epub 2010 Feb 9.
4
Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation.癌细胞中与甲基化诱导的基因沉默相关的染色质结构改变：可及性、甲基化、MeCP2结合与乙酰化的相关性
Nucleic Acids Res. 2001 Nov 15;29(22):4598-606. doi: 10.1093/nar/29.22.4598.
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Aberrant DNA methylation in cancer: potential clinical interventions.癌症中的异常DNA甲基化：潜在的临床干预措施。
Expert Rev Mol Med. 2002 Mar 4;4(4):1-17. doi: 10.1017/S1462399402004222.
6
[The most frequent methods used for DNA methylation analysis].[用于DNA甲基化分析的最常用方法]
Cas Lek Cesk. 2011;150(8):442-5.
7
Detection and interpretation of altered methylation patterns in cancer cells.癌细胞中甲基化模式改变的检测与解读。
Nat Rev Cancer. 2005 Mar;5(3):223-31. doi: 10.1038/nrc1571.
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DNA methylation ratio variability may impede clinical application of cancer diagnostic markers.
Anal Bioanal Chem. 2014 Oct;406(26):6529-37. doi: 10.1007/s00216-014-7914-5. Epub 2014 Jun 20.
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Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA.甲基化单倍型块的识别有助于对异质组织样本进行解卷积，并从血浆DNA中进行肿瘤组织起源映射。
Nat Genet. 2017 Apr;49(4):635-642. doi: 10.1038/ng.3805. Epub 2017 Mar 6.
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Predicting aberrant CpG island methylation.预测异常的CpG岛甲基化。
Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12253-8. doi: 10.1073/pnas.2037852100. Epub 2003 Sep 30.

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Methylation haplotypes of the insulin gene promoter in children and adolescents with type 1 diabetes: Can a dimensionality reduction approach predict the disease?1型糖尿病儿童和青少年胰岛素基因启动子的甲基化单倍型：降维方法能否预测该疾病？
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Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers.
使用甲基化相关模块和集成机器学习分类器预测肺腺癌疾病进展
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