Department of Trauma, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Department of Rheumatology, University Hospital Zurich, Zürich, Switzerland.
Arch Osteoporos. 2018 Jul 27;13(1):82. doi: 10.1007/s11657-018-0489-6.
This matched case-control study compared the rate of symptomatic adjacent-level vertebral compression fractures (VCF) within 1 year in patients operatively treated with kyphoplasty to a control group of non-operatively treated VCFs. The adjacent-level fracture rate did not show a significant difference between groups.
To compare the rate of new symptomatic adjacent-level fractures within 1 year after an isolated osteoporotic vertebral compression fracture (VCF) treated by either kyphoplasty or non-operative treatment.
Patients aged ≥ 50 years with an isolated, fresh, and symptomatic osteoporotic VCF who were treated by kyphoplasty were compared to patients of similar age, gender, vertebral segment, and bone mineral density who were treated non-operatively (n = 98). A matched case-control analysis was conducted by retrospective chart review, and the rate of new adjacent-level symptomatic vertebral fractures, defined as occurring within two segments of the index fracture, within the first year was determined.
Ninety-eight patients (66 female, aged 73.5, SD 9.7 years) were analyzed in this matched case-control study. The adjacent fracture rate within 1 year was not different between the kyphoplasty group and the non-operative group (20.4 vs 18.4%; McNemar, p = 1.0). The time to a new adjacent fracture after the index fracture was significantly shorter in the kyphoplasty (7, SD 8 weeks) versus non-operative group (22, SD 13 weeks).
Patients with osteoporotic VCFs treated with kyphoplasty did not show an increased rate of additional symptomatic adjacent-level VCFs when compared to a non-operative control group matched for age, gender, fracture level, and bone mineral density.
Level III.
本配对病例对照研究比较了经皮椎体后凸成形术治疗与未手术治疗的压缩性骨折（VCF）患者在 1 年内发生症状性邻近节段椎体压缩骨折（VCF）的比率。两组之间的邻近节段骨折率无显著差异。
比较经皮椎体后凸成形术与非手术治疗单独治疗骨质疏松性椎体压缩骨折（VCF）后 1 年内新发症状性邻近节段骨折的发生率。
对年龄≥50 岁、有孤立性、新鲜、有症状的骨质疏松性 VCF 患者行经皮椎体后凸成形术治疗的患者与相似年龄、性别、节段和骨密度的接受非手术治疗的患者（n=98）进行比较。通过回顾性图表审查进行配对病例对照分析，确定在索引骨折的两个节段内发生的新的邻近节段症状性椎体骨折的发生率，定义为在索引骨折后 1 年内发生。
本配对病例对照研究共分析了 98 例患者（66 例女性，年龄 73.5，标准差 9.7 岁）。在 1 年内，经皮椎体后凸成形术组和非手术组的邻近骨折率无差异（20.4%比 18.4%；McNemar，p=1.0）。与非手术组（22 周，标准差 13 周）相比，经皮椎体后凸成形术组（7 周，标准差 8 周）索引骨折后发生新的邻近骨折的时间明显更短。
与年龄、性别、骨折水平和骨密度匹配的非手术对照组相比，经皮椎体后凸成形术治疗骨质疏松性 VCF 的患者并未显示出更高的附加症状性邻近节段 VCF 发生率。
III 级。
