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前庭康复治疗对颅脑外伤后头晕和平衡问题患者的影响:一项随机对照试验。

The effects of vestibular rehabilitation on dizziness and balance problems in patients after traumatic brain injury: a randomized controlled trial.

机构信息

1 Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway.

2 Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.

出版信息

Clin Rehabil. 2019 Jan;33(1):74-84. doi: 10.1177/0269215518791274. Epub 2018 Jul 30.

DOI:10.1177/0269215518791274
PMID:30056743
Abstract

OBJECTIVE

: To investigate the effects of group-based vestibular rehabilitation in patients with traumatic brain injury.

DESIGN

: A single-blind randomized controlled trial.

SETTING

: University Hospital (recruitment and baseline assessments) and Metropolitan University (experimental intervention).

SUBJECTS

: A total of 65 patients (45 women) with mild-to-moderate traumatic brain injury (mean age 39.4 ± 13.0 years) were randomly assigned to intervention ( n = 33) or control group ( n = 32).

INTERVENTION

: Group-based vestibular rehabilitation for eight weeks. Participants were tested at baseline (3.5 ± 2.1 months after injury) and at two post-intervention follow-ups (2.7 ± 0.8 and 4.4 ± 1.0 months after baseline testing).

MAIN MEASURES

: Primary outcome: Dizziness Handicap Inventory. Secondary outcome: High-Level Mobility Assessment Tool. Other outcomes: Vertigo Symptom Scale; Rivermead Post-concussion Symptoms Questionnaire; Hospital Anxiety and Depression Scale; and Balance Error Scoring System. Between-group differences were analyzed with a linear mixed-model analysis for repeated measurements.

RESULTS

: At baseline, no group differences were revealed (personal factors, clinical characteristics and outcome measures). At the first follow-up, statistically significant mean differences in favor of the intervention were found in the primary (-8.7, 95% confidence interval (CI): -16.6 to -0.9) and secondary outcomes (3.7 points, 95% CI: 1.4-6.0). At the second follow-up, no significant between-group differences were found. No significant between-group differences in the other outcomes were found at the two follow-ups.

CONCLUSION

: The intervention appeared to speed up recovery for patients with dizziness and balance problems after traumatic brain injury. However, the benefits had dissipated two months after the end of the intervention.

摘要

目的

研究基于小组的前庭康复对创伤性脑损伤患者的影响。

设计

单盲随机对照试验。

地点

大学医院(招募和基线评估)和大都市大学(实验干预)。

对象

共 65 例(45 名女性)轻度至中度创伤性脑损伤患者(平均年龄 39.4 ± 13.0 岁),随机分为干预组(n = 33)和对照组(n = 32)。

干预

为期 8 周的基于小组的前庭康复。参与者在基线(受伤后 3.5 ± 2.1 个月)和 2 次干预后随访(基线测试后 2.7 ± 0.8 和 4.4 ± 1.0 个月)时进行测试。

主要观察指标

主要结局:眩晕障碍量表。次要结局:高级移动能力评估工具。其他结局:眩晕症状量表;Rivermead 脑震荡后症状问卷;医院焦虑和抑郁量表;平衡错误评分系统。采用重复测量线性混合模型分析比较组间差异。

结果

基线时,两组间无差异(个人因素、临床特征和结局测量)。在第一次随访时,干预组在主要结局(-8.7,95%置信区间(CI):-16.6 至 -0.9)和次要结局(3.7 分,95% CI:1.4-6.0)上显示出统计学上的显著优势。在第二次随访时,两组间无显著差异。在两次随访中,其他结局均无显著组间差异。

结论

该干预似乎可以加快创伤性脑损伤后伴有头晕和平衡问题患者的康复速度。然而,干预结束两个月后,益处就消失了。

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