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体重指数与择期食管裂孔疝修补术后结局的关系。

The Association of Body Mass Index with Postoperative Outcomes After Elective Paraesophageal Hernia Repair.

机构信息

Department of Surgery, Division of Gastrointestinal Surgery, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA.

Department of Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

出版信息

J Gastrointest Surg. 2018 Dec;22(12):2029-2036. doi: 10.1007/s11605-018-3853-3. Epub 2018 Jul 31.

DOI:10.1007/s11605-018-3853-3
PMID:30066068
Abstract

PURPOSE

To evaluate the association between body mass index (BMI) and postoperative outcomes in elective paraesophageal hernia (PEH) repairs.

METHODS

A retrospective review of patients who underwent elective PEH repair in the ACS NSQIP database (2005-2015) was performed. Patients were stratified into BMI groups (< 18.5, 18.5-24.9, 25.0-29.9, 30.0-34.9, 35-39.9, and ≥ 40.0 kg/m) according to the World Health Organization classification criteria. A multivariable logistic regression model was developed to characterize the association between BMI class and outcomes, including readmission, reoperation, postoperative complications, and mortality.

RESULTS

The median (IQR) age of the 9641 patients who met inclusion criteria was 64 (55-72) and 72.7% were women. Across each BMI class, age, race, gender, type of procedure, frailty index, smoking, and ASA class varied (p < 0.05). Underweight patients (BMI < 18.5 kg/m) had an increased risk of mortality (OR = 6.35, p < 0.05). Patients with a BMI 35-39.9 kg/m (OR = 0.65, p < 0.05) and ≥ 40 kg/m (OR = 0.36, p < 0.001) were associated with a decreased risk for readmissions.

CONCLUSION

Underweight patients have an increased risk for postoperative mortality after elective PEH repair. Higher BMI was associated with a diminished risk for readmission, but not for mortality, reoperations, or overall complications.

摘要

目的

评估体质量指数(BMI)与择期食管裂孔疝(PEH)修复术后结局的关系。

方法

对 ACS NSQIP 数据库(2005-2015 年)中接受择期 PEH 修复的患者进行回顾性分析。根据世界卫生组织分类标准,患者分为 BMI 组(<18.5、18.5-24.9、25.0-29.9、30.0-34.9、35-39.9 和≥40.0 kg/m)。采用多变量逻辑回归模型描述 BMI 类别与结局(包括再入院、再次手术、术后并发症和死亡率)之间的关系。

结果

符合纳入标准的 9641 例患者的中位(IQR)年龄为 64(55-72)岁,其中 72.7%为女性。在每个 BMI 类别中,年龄、种族、性别、手术类型、虚弱指数、吸烟和 ASA 分级均存在差异(p<0.05)。体重不足患者(BMI<18.5 kg/m)的死亡率增加(OR=6.35,p<0.05)。BMI 为 35-39.9 kg/m(OR=0.65,p<0.05)和≥40 kg/m(OR=0.36,p<0.001)的患者再入院风险降低。

结论

择期 PEH 修复后,体重不足患者的术后死亡率增加。较高的 BMI 与再入院风险降低相关,但与死亡率、再次手术、总并发症无关。

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同期减重手术与食管裂孔疝修补术:袖状胃切除术与 Roux-en-Y 胃旁路术的比较。
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A 5-item frailty index based on NSQIP data correlates with outcomes following paraesophageal hernia repair.基于国家外科质量改进计划(NSQIP)数据的五项衰弱指数与食管旁疝修补术后的结果相关。
Surg Endosc. 2017 Jun;31(6):2509-2519. doi: 10.1007/s00464-016-5253-7. Epub 2016 Oct 3.
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The impact of frailty on outcomes of paraesophageal hernia repair.衰弱对食管旁疝修补术结局的影响。
J Surg Res. 2016 May 15;202(2):259-66. doi: 10.1016/j.jss.2016.02.042. Epub 2016 Mar 4.
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Emergent Surgery Does Not Independently Predict 30-Day Mortality After Paraesophageal Hernia Repair: Results from the ACS NSQIP Database.急诊手术并非食管旁疝修补术后30天死亡率的独立预测因素:美国外科医师学会国家外科质量改进计划数据库的结果
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Morbidity and Mortality Associated With Elective or Emergency Paraesophageal Hernia Repair.择期或急诊食管旁疝修补术相关的发病率和死亡率
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The obesity paradox in stroke: lower mortality and lower risk of readmission for recurrent stroke in obese stroke patients.中风中的肥胖悖论:肥胖中风患者的死亡率较低且复发性中风再入院风险较低。
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