Department of Surgery, Division of Gastrointestinal Surgery, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA.
Department of Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
J Gastrointest Surg. 2018 Dec;22(12):2029-2036. doi: 10.1007/s11605-018-3853-3. Epub 2018 Jul 31.
To evaluate the association between body mass index (BMI) and postoperative outcomes in elective paraesophageal hernia (PEH) repairs.
A retrospective review of patients who underwent elective PEH repair in the ACS NSQIP database (2005-2015) was performed. Patients were stratified into BMI groups (< 18.5, 18.5-24.9, 25.0-29.9, 30.0-34.9, 35-39.9, and ≥ 40.0 kg/m) according to the World Health Organization classification criteria. A multivariable logistic regression model was developed to characterize the association between BMI class and outcomes, including readmission, reoperation, postoperative complications, and mortality.
The median (IQR) age of the 9641 patients who met inclusion criteria was 64 (55-72) and 72.7% were women. Across each BMI class, age, race, gender, type of procedure, frailty index, smoking, and ASA class varied (p < 0.05). Underweight patients (BMI < 18.5 kg/m) had an increased risk of mortality (OR = 6.35, p < 0.05). Patients with a BMI 35-39.9 kg/m (OR = 0.65, p < 0.05) and ≥ 40 kg/m (OR = 0.36, p < 0.001) were associated with a decreased risk for readmissions.
Underweight patients have an increased risk for postoperative mortality after elective PEH repair. Higher BMI was associated with a diminished risk for readmission, but not for mortality, reoperations, or overall complications.
评估体质量指数(BMI)与择期食管裂孔疝(PEH)修复术后结局的关系。
对 ACS NSQIP 数据库(2005-2015 年)中接受择期 PEH 修复的患者进行回顾性分析。根据世界卫生组织分类标准,患者分为 BMI 组(<18.5、18.5-24.9、25.0-29.9、30.0-34.9、35-39.9 和≥40.0 kg/m)。采用多变量逻辑回归模型描述 BMI 类别与结局(包括再入院、再次手术、术后并发症和死亡率)之间的关系。
符合纳入标准的 9641 例患者的中位(IQR)年龄为 64(55-72)岁,其中 72.7%为女性。在每个 BMI 类别中,年龄、种族、性别、手术类型、虚弱指数、吸烟和 ASA 分级均存在差异(p<0.05)。体重不足患者(BMI<18.5 kg/m)的死亡率增加(OR=6.35,p<0.05)。BMI 为 35-39.9 kg/m(OR=0.65,p<0.05)和≥40 kg/m(OR=0.36,p<0.001)的患者再入院风险降低。
择期 PEH 修复后,体重不足患者的术后死亡率增加。较高的 BMI 与再入院风险降低相关,但与死亡率、再次手术、总并发症无关。