Department of Neuroscience, Inova Health System, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA.
Division of Neuro-Oncology, University of Virginia Health System, 1300 Jefferson Park Avenue, West Complex, Room 6228, Charlottesville, VA 22903-0156, USA.
Neurol Clin. 2018 Aug;36(3):449-466. doi: 10.1016/j.ncl.2018.04.004. Epub 2018 May 29.
Patients with brain tumor encounter a wide spectrum of tumor and treatment-related complications during their disease course. Tumors may serve as seizure substrates, are associated with a hypercoagulable state that results in thromboembolic complications, and may influence mood and cognition. Antitumor and supportive therapies may also have deleterious effects. Herein, we discuss major aspects of supportive care for patients with brain tumors, with attention to benefit and complications derived from the management of seizures, brain edema, venous thromboembolism, fatigue, mood alterations, and cognitive dysfunction.
脑肿瘤患者在疾病过程中会遇到广泛的肿瘤和治疗相关并发症。肿瘤可能成为癫痫发作的基础,与导致血栓栓塞并发症的高凝状态有关,并且可能影响情绪和认知。抗肿瘤和支持性治疗也可能产生有害影响。在此,我们讨论了脑肿瘤患者支持性护理的主要方面,重点关注癫痫发作、脑水肿、静脉血栓栓塞、疲劳、情绪改变和认知功能障碍的管理所带来的益处和并发症。