Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Neurol Clin. 2018 Aug;36(3):579-598. doi: 10.1016/j.ncl.2018.04.011. Epub 2018 Jun 15.
Neurologic complications of cancer may involve both the central nervous system and peripheral nervous system manifesting as brain, leptomeningeal, intramedullary, intradural, epidural, plexus, and skull base metastases. Excluding brain involvement, neurologic complications affecting these other sites are relatively infrequent, but collectively they affect more than 25% of patients with metastatic cancer causing significant morbidity and mortality. Early diagnosis and intervention optimize quality of life and improve survival.
癌症的神经系统并发症可能涉及中枢神经系统和周围神经系统,表现为脑、软脑膜、脊髓内、硬脊膜内、硬膜外、神经丛和颅底转移。不包括脑转移,影响这些其他部位的神经系统并发症相对较少见,但它们共同影响超过 25%的转移性癌症患者,导致严重的发病率和死亡率。早期诊断和干预可优化生活质量并提高生存率。