Sarikaya Ismet, Sarikaya Ali, Elgazzar Abdelhamid H
Department of Nuclear Medicine, Kuwait University Faculty of Medicine, Safat, Kuwait; and
Department of Nuclear Medicine, Trakya University Faculty of Medicine, Edirne, Turkey
J Nucl Med Technol. 2018 Dec;46(4):362-367. doi: 10.2967/jnmt.118.210237. Epub 2018 Aug 3.
F-FDG PET brain imaging is commonly used in the early detection and differential diagnosis of various subtypes of dementias. F-FDG PET images are mainly evaluated visually, and semiquantitative analysis programs are also commonly used in many centers. However, visual and semiquantitative analysis carry certain limitations. Visual assessment is subjective and dependent on expertise. Commercially available semiquantitative analysis programs have certain limitations such as suboptimal selection of brain areas or erroneous uptake normalization procedures that may provide inaccurate results, and physicians reporting semiquantitative results should be aware of these. In this pictorial review article, we will discuss the current status of F-FDG PET brain imaging in patients with dementia and present figures and semiquantitative analysis results of various subtypes of dementias as well as certain artifacts seen on F-FDG PET brain imaging studies.
氟代脱氧葡萄糖正电子发射断层扫描（F-FDG PET）脑成像常用于各种类型痴呆的早期检测和鉴别诊断。F-FDG PET图像主要通过视觉评估，许多中心也普遍使用半定量分析程序。然而，视觉和半定量分析存在一定局限性。视觉评估具有主观性且依赖专业知识。市售的半定量分析程序存在某些局限性，如脑区选择欠佳或摄取归一化程序有误，可能导致结果不准确，报告半定量结果的医生应了解这些情况。在这篇图片综述文章中，我们将讨论痴呆患者F-FDG PET脑成像的现状，并展示各种类型痴呆的图像和半定量分析结果，以及F-FDG PET脑成像研究中出现的某些伪影。
