Center for Orthopedics and Trauma Surgery, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, Germany.
Institute of Medical Biometry and Epidemiology, University Marburg, Bunsenstraße 3, 35037, Marburg, Germany.
Int Orthop. 2019 Mar;43(3):653-658. doi: 10.1007/s00264-018-4047-z. Epub 2018 Aug 3.
In this study, the total blood loss, transfusion rate and number of transfused blood units in patients with different indications for shoulder arthroplasty: primary, fracture and secondary were compared. Risk factors for bleeding and transfusion were analysed.
Medical records and the database of the institution's blood bank from 527 patients that received shoulder arthroplasty were analysed retrospectively. This study included 419 patients that were divided in three different groups: primary (n = 278), fracture (n = 110) and secondary (following prior osteosynthesis; n = 31) shoulder arthroplasty. The demographic and clinical data were collected. The total blood loss (TBL) was calculated and transfusions recorded.
The transfusion rate and mean amount of transfused blood units (BU) were higher in fracture (32.7% and 0.69BU, p < 0.01) and secondary arthroplasty (35.5% and 0.97BU, p < 0.01) than in primary arthroplasty (12.6% and 0.28BU). The overall transfusion rate was 19.6% at a mean TBL of 370 ml. However, patients with primary arthroplasty experienced significantly higher total blood loss than those after fracture arthroplasty (p < 0.01). Longer surgery time and male sex are significant risk factors for elevated blood loss. The pre-operative use of vitamin K antagonist, cemented arthroplasty, high BMI, coronary heart disease and ASA score > 2 are relevant risk factors for blood transfusion.
The most important susceptible factor that affects the TBL is the surgery time. Transfusion rates are higher in patients with fracture arthroplasty than after primary arthroplasty.
本研究比较了不同肩关节置换适应证(原发性、骨折和继发性)患者的总失血量、输血率和输血量。分析了出血和输血的危险因素。
回顾性分析了 527 例接受肩关节置换术患者的病历和机构血库数据库。本研究包括 419 例患者,分为三组:原发性(n=278)、骨折(n=110)和继发性(既往骨愈合术后;n=31)肩关节置换。收集了患者的人口统计学和临床资料。计算总失血量(TBL)并记录输血情况。
骨折(32.7%和 0.69BU,p<0.01)和继发性(35.5%和 0.97BU,p<0.01)肩关节置换的输血率和平均输血量(BU)均高于原发性肩关节置换(12.6%和 0.28BU)。总体输血率为 19.6%,平均 TBL 为 370ml。然而,原发性肩关节置换患者的总失血量明显高于骨折后肩关节置换患者(p<0.01)。手术时间较长和男性是出血增加的显著危险因素。术前使用维生素 K 拮抗剂、骨水泥型关节置换、高 BMI、冠心病和 ASA 评分>2 是输血的相关危险因素。
影响 TBL 的最重要易感因素是手术时间。骨折后肩关节置换患者的输血率高于原发性肩关节置换。