Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education); National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, Hunan Normal University, Changsha 410081, P. R. China.
Chem Commun (Camb). 2018 Aug 21;54(68):9430-9433. doi: 10.1039/c8cc05590d.
Intrachain TiIV-oxazoline complexation together with hydrophobic interaction triggered the self-folding of an oxazoline-containing single polymeric chain in water. The formed TiIV-folded single-chain polymeric nanoparticles (SCPNs) acted as metalloenzyme-mimetic catalysts in asymmetric sulfoxidation in water owing to their organized, compartmentalized structure, effective site isolation, and also secondary coordination sphere provided by a copolymer backbone. In addition, they also could be facilely recovered for reuse by simple thermo-controlled separation.
链内 TiIV-恶唑啉络合作用加上疏水相互作用引发了含恶唑啉的单链聚合物在水中的自折叠。形成的 TiIV 折叠的单链聚合物纳米粒子 (SCPNs) 由于其有序的、分隔的结构、有效的位点隔离以及共聚物主链提供的次级配位球，在水中的不对称氧化反应中充当金属酶模拟催化剂。此外，它们还可以通过简单的热控分离方便地回收再利用。
