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早期膝骨关节炎患者步态再训练即刻和短期的膝关节力矩和症状的影响:一项随机对照试验。

Immediate and short-term effects of gait retraining on the knee joint moments and symptoms in patients with early tibiofemoral joint osteoarthritis: a randomized controlled trial.

机构信息

Gait & Motion Analysis Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong.

Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong.

出版信息

Osteoarthritis Cartilage. 2018 Nov;26(11):1479-1486. doi: 10.1016/j.joca.2018.07.011. Epub 2018 Aug 3.

Abstract

OBJECTIVE

To evaluate the effectiveness of a knee adduction moment (KAM) gait retraining in patients with early knee osteoarthritis up to 6 months post-training.

METHOD

We conducted a single blinded randomized controlled trial on a total of 23 patients with early knee osteoarthritis who were randomly allocated to the gait retraining group and walking exercise group. Twenty of them completed the corresponding training and the 6-month evaluation. We measured KAM, knee flexion moment (KFM) and western ontario and McMaster universities osteoarthritis index (WOMAC) osteoarthritis index before, immediate after, and 6 months after training. A repeated measures analysis of covariance (ANCOVA) was used to compare KAM, KFM and WOMAC osteoarthritis index scores across the three time points i.e., pre-training, post-training, and 6-month follow-up with gender, knee osteoarthritis severity, and pre-training KAM, KFM and WOMAC scores set as covariates. Post-hoc analyses were conducted when indicated.

RESULTS

Significant time × group interactions were found for both KAM and WOMAC osteoarthritis index scores (P < 0.002). No interaction was found for KFM (P = 0.123). KAM after gait retraining was significantly lower than the pre-training value (P < 0.001) and such effect was maintained at 6-month follow-up (P = 0.01). There was no significant difference in the KAM across time in the walking exercise group (P > 0.208). WOMAC osteoarthritis index score after training and score at the 6-month follow-up were significantly improved in the gait retraining group (P = 0.001), while the WOMAC osteoarthritis index score remained similar.

CONCLUSIONS

Gait retraining is an effective intervention to reduce KAM during walking and to improve the symptoms of patients with early knee osteoarthritis in short term.

摘要

目的

评估膝关节内收力矩(KAM)步态再训练对早期膝关节骨关节炎患者的疗效,随访时间为训练后 6 个月。

方法

我们对 23 例早期膝关节骨关节炎患者进行了单盲随机对照试验,将其随机分为步态再训练组和步行运动组。其中 20 例完成了相应的训练和 6 个月的评估。我们在训练前、训练后即刻和训练后 6 个月测量了 KAM、膝关节屈曲力矩(KFM)和西安大略和麦克马斯特大学骨关节炎指数(WOMAC)骨关节炎指数。采用重复测量方差分析(ANCOVA)比较了 3 个时间点(即训练前、训练后和 6 个月随访)的 KAM、KFM 和 WOMAC 骨关节炎指数评分,性别、膝关节骨关节炎严重程度以及训练前 KAM、KFM 和 WOMAC 评分作为协变量。需要时进行了事后分析。

结果

KAM 和 WOMAC 骨关节炎指数评分均显示出显著的时间×组间交互作用(P<0.002)。KFM 无交互作用(P=0.123)。步态再训练后的 KAM 明显低于训练前(P<0.001),且在 6 个月随访时仍保持(P=0.01)。步行运动组的 KAM 在不同时间点无显著差异(P>0.208)。步态再训练组训练后和 6 个月随访时的 WOMAC 骨关节炎指数评分均显著改善(P=0.001),而 WOMAC 骨关节炎指数评分保持不变。

结论

步态再训练是一种有效的干预措施,可以降低膝关节骨关节炎患者行走时的 KAM,改善其短期症状。

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