Louis J C, Anglard P, Vincendon G
Presse Med. 1986 Feb 1;15(4):157-60.
The adrenocorticotropic hormone (ACTH) is produced within the cell body of hypothalamic neurons by proteolytic cleavage of its large precursor molecule, pro-opiomelanocortin. These neurons distribute ACTH-containing nerve endings throughout the central nervous system. ACTH is able to evoke motor and behavioural responses and to modify neuronal metabolism. Since ACTH has been shown to regulate glucose uptake and utilization, its implication in the adaptative response to stress situations, such as cerebral hypoxia, deserves further investigations.
促肾上腺皮质激素（ACTH）由其大分子前体分子阿黑皮素原在丘脑下部神经元的细胞体内经蛋白水解裂解产生。这些神经元将含有ACTH的神经末梢分布于整个中枢神经系统。ACTH能够引发运动和行为反应，并改变神经元代谢。由于已证明ACTH可调节葡萄糖摄取和利用，因此其在对诸如脑缺氧等应激情况的适应性反应中的作用值得进一步研究。
