Carmina E, Rosato F, Caputo A, Janní A
Acta Eur Fertil. 1985 Nov-Dec;16(6):427-30.
3 patients with late-onset 3 beta-HSD deficiency are described. They presented increased DHEAs/delta 4 ratio either in basal conditions or after ACTH stimulation. All patients were hirsute but only one had increased serum values of delta 4 and total testosterone. However, all patients presented increased serum levels of free testosterone. Two patients had normal menstrual cycles and in one case a secondary PCO was found.
本文描述了3例迟发性3β-羟类固醇脱氢酶（3β-HSD）缺乏症患者。他们在基础状态或促肾上腺皮质激素（ACTH）刺激后，脱氢表雄酮硫酸盐（DHEAs）/Δ4比值升高。所有患者均多毛，但只有1例患者的血清Δ4和总睾酮值升高。然而，所有患者的血清游离睾酮水平均升高。2例患者月经周期正常，1例发现继发性多囊卵巢。
