Glybochko P V, Fisenko V P
Eksp Klin Farmakol. 2016;79(10):34-43.
Data on the principles of BCG vaccine action on the cancer of bladder are presented. Probable targets for BCG vaccine are estimated. Efficacy of BCG vaccine in non-muscle invasive cancer of bladder is analyzed. Side effects of BCG vaccine are examined. Possibilities of evaluating BCG vaccine usage at low (sub-therapeutical) doses are discussed. Various approaches to reducing the resistance of bladder cancer with respect to BCG vaccine are considered. The perspectives of bladder cancer immunotherapy are outlined.
本文介绍了卡介苗（BCG）疫苗对膀胱癌作用原理的数据。估计了BCG疫苗可能的作用靶点。分析了BCG疫苗在非肌层浸润性膀胱癌中的疗效。研究了BCG疫苗的副作用。讨论了评估低（亚治疗）剂量BCG疫苗使用的可能性。考虑了降低膀胱癌对BCG疫苗耐药性的各种方法。概述了膀胱癌免疫治疗的前景。
