冠状动脉搭桥手术中德尔尼多停搏液与间歇性温血心脏停搏液的比较
Comparison of Del Nido and Intermittent Warm Blood Cardioplegia in Coronary Artery Bypass Grafting Surgery.
作者信息
Ucak Haci Ali, Uncu Hasan
机构信息
Department of Cardiovascular Surgery, University of Health Sciences Adana City Hospital, Adana, Turkey.
出版信息
Ann Thorac Cardiovasc Surg. 2019 Feb 20;25(1):39-45. doi: 10.5761/atcs.oa.18-00087. Epub 2018 Aug 9.
Abstract
PURPOSE
In this study, we aim to investigate the efficacy and clinical results of using Del Nido solution (DNS) in coronary artery bypass grafting (CABG) surgery by comparing with intermittent warm blood cardioplegia (IWBC).
METHODS
Between March 2017 and February 2018, 297 adult patients who underwent primary isolated CABG surgery with cardiopulmonary bypass (CPB) were included in the study. We used DNS in 112 patients and IWBC was used in 185 patients. We compared both the clinical and the laboratory results.
RESULTS
Aortic cross-clamp time, CPB time, and peak glucose level are lower with DNS. But we did not observe any meaningful difference of clinical results between two methods including postoperative myocardial enzyme release.
CONCLUSION
Del Nido cardioplegia was developed for immature heart and pediatric surgery. But in our opinion, it is a good and useful alternative to CABG surgery with similar results to IWBC.
摘要
目的
在本研究中，我们旨在通过与间歇性温血心脏停搏液（IWBC）比较，探讨在冠状动脉旁路移植术（CABG）中使用德尔尼多溶液（DNS）的疗效和临床结果。
方法
2017年3月至2018年2月期间，297例接受体外循环（CPB）下初次单纯CABG手术的成年患者纳入本研究。112例患者使用DNS，185例患者使用IWBC。我们比较了临床和实验室结果。
结果
使用DNS时，主动脉阻断时间、CPB时间和血糖峰值水平较低。但我们未观察到两种方法在临床结果上有任何有意义的差异，包括术后心肌酶释放。
结论
德尔尼多心脏停搏液是为未成熟心脏和小儿手术开发的。但在我们看来，它是CABG手术的一种良好且有用的替代方法，其结果与IWBC相似。
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