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使用植入式心脏监测器进行长期监测以检测心房颤动。

Long-term monitoring to detect atrial fibrillation with the indwelling implantable cardiac monitors.

机构信息

Universita Cattolica del Sacro Cuore, Rome, Italy.

出版信息

Int J Stroke. 2018 Dec;13(9):893-904. doi: 10.1177/1747493018790023. Epub 2018 Aug 9.

Abstract

An increasing number of detection tools are available and several detection strategies have been described to pursue the diagnosis of atrial fibrillation to prevent ischemic stroke. Monitoring tools include standard electrocardiography, snapshot single-lead recordings with professional or personal devices (e.g. smartphone-based), Holter monitor, external devices with long-term recording capabilities, and cardiac implantable electronic devices, including pacemakers, implantable cardioverter defibrillators and insertable cardiac monitors. Insertable cardiac monitors have shown high sensitivity and specificity for the detection of atrial fibrillation, allow up to three years of continuous monitoring, do not require cooperation of the patient, are well tolerated, have a short device-related time delay between detection of atrial fibrillation and notification to the physician, provide information on atrial fibrillation burden and are minimally invasive. On the other hand, insertable cardiac monitors require a considerable use of resources to process the recordings and have a significant initial cost. Studies conducted with insertable cardiac monitors on patients with prior stroke and on patients with risk factors for stroke but no prior cerebrovascular events or atrial fibrillation have consistently shown a measurable incidence of atrial fibrillation at follow-up. However, the effectiveness of oral anticoagulations in reducing the incidence of ischemic stroke in patients with atrial fibrillation lasting less than 24 h, though reasonable, is currently unproven. The future of atrial fibrillation detection tools and atrial fibrillation detection strategies will be influenced by ongoing studies exploring whether oral anticoagulations reduce the incidence of stroke in patients with atrial fibrillation burden lower than 24 h.

摘要

越来越多的检测工具已经可用,并且已经描述了几种检测策略来追求心房颤动的诊断以预防缺血性中风。监测工具包括标准心电图、使用专业或个人设备(例如基于智能手机的)的单导联快照记录、动态心电图监测仪、具有长期记录能力的外部设备以及心脏植入式电子设备,包括起搏器、植入式除颤器和可植入心脏监测器。可植入心脏监测器在检测心房颤动方面具有较高的敏感性和特异性,可进行长达三年的连续监测,不需要患者的配合,耐受良好,在检测到心房颤动并通知医生之间的设备相关时间延迟短,提供有关心房颤动负担的信息,并且微创。另一方面,可植入心脏监测器需要大量资源来处理记录,并且初始成本很高。在先前患有中风的患者和有中风风险因素但无先前脑血管事件或心房颤动的患者中进行的可植入心脏监测器研究一致表明,在随访中可测量到心房颤动的发生率。然而,口服抗凝剂在减少持续时间小于 24 小时的心房颤动患者中缺血性中风发生率的有效性虽然合理,但目前尚未得到证实。正在进行的研究探索口服抗凝剂是否可以降低心房颤动负担低于 24 小时的患者中风发生率,这将影响心房颤动检测工具和心房颤动检测策略的未来。

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