Ioannidis Argyrios, Konstantinidis Michael, Apostolakis Sotirios, Koutserimpas Christos, Machairas Nikolaos, Konstantinidis Konstantinos M
Department of General, Laparoscopic, Robotic and Bariatric Surgery, Athens Medical Center, 15125 Athens, Greece.
National and Kapodistrian University of Athens, School of Medicine, 11527 Athens, Greece.
Mol Clin Oncol. 2018 Aug;9(2):135-137. doi: 10.3892/mco.2018.1658. Epub 2018 Jun 15.
Οncological outcomes in patients with primary rectal cancer have markedly improved over the last few years, mainly due to the widespread application of the total mesorectal excision technique. This improvement should also be largely attributed to multiple specialties, other than colorectal surgery, such as radiology, oncology and pathology. Therefore, a multimodal approach is key to efficient and appropriate rectal cancer management. Multidisciplinary tumor (MDT) boards have become an important asset for the management and treatment of patients with rectal cancer, and a number of studies published to date suggest the beneficial effect of the multidisciplinary approach on the management of such patients. The available evidence demonstrates a modification of the treatment plan, attributed to the MDT implementation, in a non-negligible proportion of these patients. However, more studies are required in order to assess the exact impact of MDT boards on disease-free and overall survival of patients with primary rectal cancer.
在过去几年中,原发性直肠癌患者的肿瘤学结局有了显著改善,这主要归功于全直肠系膜切除术技术的广泛应用。这种改善在很大程度上也应归功于除结直肠外科之外的多个专业领域,如放射学、肿瘤学和病理学。因此,多模式方法是有效且恰当管理直肠癌的关键。多学科肿瘤(MDT)委员会已成为直肠癌患者管理和治疗的一项重要资产,迄今为止发表的一些研究表明多学科方法对此类患者的管理具有有益效果。现有证据表明,在这些患者中,有不可忽视的一部分患者因实施MDT而修改了治疗方案。然而,为了评估MDT委员会对原发性直肠癌患者无病生存期和总生存期的确切影响,还需要更多研究。