Richardson J D, Aust J B
Ann Surg. 1977 Jun;185(6):649-55. doi: 10.1097/00000658-197706000-00006.
Due to poor results with conventional operative therapy for diffuse hemorrhagic gastritis (DHG), a prospective evaluation of gastric devascularization was performed on 21 patients. Sepsis, alcoholism, and steroid abuse were the common etiologic factors. In spite of the fact that these were all critically ill patients, all stopped bleeding with this operation and only two rebled (9%). The average operating time was 84 minutes. There were two operative complications and gastric necrosis did not occur. The mortality was high (38%) due to the primary disease. Gastric devascularization is a useful salvage procedure for the patient with DHG because it can be accomplished rapidly, with few complications, has a low rebleed rate, and causes no permanent sequelae. Since this procedure causes severe gastric mucosal ischemia, it casts doubt only on the importance of this mechanism alone as the cause of "stress ulceration."
由于传统手术疗法治疗弥漫性出血性胃炎(DHG)效果不佳,对21例患者进行了胃去血管化的前瞻性评估。脓毒症、酗酒和滥用类固醇是常见病因。尽管这些患者病情都很危重,但所有患者经此手术后出血均停止,仅有2例再次出血(9%)。平均手术时间为84分钟。有2例手术并发症,未发生胃坏死。因原发性疾病死亡率较高(38%)。胃去血管化对于DHG患者是一种有效的挽救性手术,因为它操作迅速,并发症少,再出血率低,且不会导致永久性后遗症。由于该手术会导致严重的胃黏膜缺血,这仅使人怀疑这一机制本身作为“应激性溃疡”病因的重要性。