Sürmeli-Döven Serra, Delibaş Ali, Gürses İclal, Kayacan Uğur Raşit, Coşkun-Yılmaz Banu, Esen Kaan, Korkmaz Emine, Özaltın Fatih
Departments of Pediatric Nephrology, Mersin University Faculty of Medicine, Mersin, Turkey.
Departments of Pathology, Mersin University Faculty of Medicine, Mersin, Turkey.
Turk J Pediatr. 2018;60(1):81-85. doi: 10.24953/turkjped.2018.01.012.
Sürmeli-Döven S, Delibaş A, Gürses İ, Kayacan UR, Coşkun-Yılmaz B, Esen K, Korkmaz E, Özaltın F. Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not? Turk J Pediatr 2018; 60: 81-85. A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings. His stool was negative for Shiga toxin producing E. coli (STEC). During follow-up he developed respiratory distress, hypertrophic cardiomyopathy and seizure. His genetic tests for atypical HUS (aHUS) were negative. His clinical and histological findings indicated hemolytic uremic syndrome and immunglobulin A nephropathy (IgAN). The patient responded to steroid treatment and plasma exchange therapy with peritoneal dialysis. We discuss the probable connection between HUS and IgAN.
