伴有恶性神经元成分的小儿原发性间变性节细胞胶质瘤

Pediatric primary anaplastic ganglioglioma with malignant neuronal component.

作者信息

Kaymak-Cihan Meriç, Erdiş Eda, Bozkurt Süheyla, Ünver-Korğalı Elif

机构信息

Departments of Pediatric Hematology and Oncology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.

Departments of Radiation Oncology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.

出版信息

Turk J Pediatr. 2018;60(1):102-106. doi: 10.24953/turkjped.2018.01.017.

DOI:10.24953/turkjped.2018.01.017

PMID:30102489

Abstract

Kaymak-Cihan M, Erdiş E, Bozkurt S, Ünver-Korğalı E. Pediatric primary anaplastic ganglioglioma with malignant neuronal component. Turk J Pediatr 2018; 60: 102-106. Gangliogliomas (GGs) represent approximately 0.4%-1.0% of all brain tumors. Anaplastic gangliogliomas (AGGs) form 5-10% of all GGs. They are a mixed neuronal-glial tumor of central nervous system and composed by two cell lines; neuronal (ganglionic) and glial cells. Anaplastic component of AGGs is usually glial cells. Malignant neuronal component is a rare condition. Here we report an 8-year-old male patient who was diagnosed with primary AGG with malignant neuronal component and was treated with surgery, adjuvant radiotherapy and chemotherapy.

摘要

凯马克 - 吉汉·M、埃尔迪什·E、博兹库尔特·S、云弗 - 科尔加利·E。伴有恶性神经元成分的小儿原发性间变性节细胞胶质瘤。《土耳其儿科学杂志》2018年；60: 102 - 106。节细胞胶质瘤（GGs）约占所有脑肿瘤的0.4% - 1.0%。间变性节细胞胶质瘤（AGGs）占所有GGs的5% - 10%。它们是中枢神经系统的一种混合性神经元 - 胶质肿瘤，由两种细胞系组成；神经元（神经节）细胞和胶质细胞。AGGs的间变成分通常是胶质细胞。恶性神经元成分是一种罕见情况。在此，我们报告一名8岁男性患者，他被诊断为伴有恶性神经元成分的原发性AGG，并接受了手术、辅助放疗和化疗。