Sitting cross-legged for 30 min alters lower limb shear stress pattern but not flow-mediated dilation or arterial stiffness.

Prolonged sitting decreases lower limb endothelial function via sustained reductions in mean shear rate. We tested whether 30 min of sitting cross-legged differentially impacts superficial femoral artery shear rate pattern, flow-mediated dilation (FMD), and leg pulse-wave velocity (PWV) compared with sitting flat-footed. Sitting cross-legged attenuated the reduction in mean and antegrade shear rate and increased arterial pressure compared with sitting flat-footed. Superficial femoral artery FMD and leg PWV were unaltered following either sitting position.