Freeny P C, Marks W M
Radiology. 1986 Jun;159(3):685-91. doi: 10.1148/radiology.159.3.3010374.
Twenty-seven perfusion abnormalities were detected in 17 of 50 patients who underwent computed tomographic angiography (CTA) of the liver. All but one of the perfusion abnormalities occurred in patients with primary or metastatic liver tumors. Perfusion abnormalities were lobar in nine cases, segmental in 11, and subsegmental in seven; 14 were hypoperfusion and 13 were hyperperfusion abnormalities. The causes for the abnormalities included nonperfusion of a replaced hepatic artery (n = 11), cirrhosis and nodular regeneration (n = 3), altered hepatic hemodynamics (e.g., siphoning, laminar flow) caused by tumor (n = 7), contrast media washout from a nonperfused vessel (n = 1), compression of adjacent hepatic parenchyma (n = 1), and unknown (n = 4). Differentiation of perfusion abnormalities from tumor usually can be made by comparing the morphology of the known tumor with the suspected perfusion abnormality, changes of each on delayed CTA scans, and review of initial angiograms and other imaging studies.
在接受肝脏计算机断层血管造影（CTA）的50例患者中，有17例检测到27处灌注异常。除1例灌注异常外，其余均发生在原发性或转移性肝肿瘤患者中。灌注异常9例为叶性，11例为节段性，7例为亚节段性；14例为灌注不足，13例为灌注过度异常。异常原因包括替代肝动脉未灌注（n = 11）、肝硬化和结节性再生（n = 3）、肿瘤引起的肝血流动力学改变（如虹吸、层流）（n = 7）、非灌注血管的造影剂洗脱（n = 1）、相邻肝实质受压（n = 1）以及原因不明（n = 4）。通常可通过比较已知肿瘤的形态与疑似灌注异常、延迟CTA扫描时各自的变化以及回顾初始血管造影和其他影像学检查来区分灌注异常与肿瘤。
