Yamamoto Yorito, Wakikawa Akiko, Ueno Akiko, Nagai Ryuhei, Matsumoto Mitsuhiro, Komatsu Junko, Kinoshita Hiromi, Minami Susumu, Hayashi Kazutoshi
Department of Obstetrics and Gynecology, Kochi Health Sciences Center, 2125 Ike, Kochi 781-8555, Japan.
Department of Obstetrics and Gynecology, Kochi Health Sciences Center, 2125 Ike, Kochi 781-8555, Japan.
Cancer Treat Res Commun. 2018;14:26-29. doi: 10.1016/j.ctarc.2017.11.002. Epub 2017 Nov 13.
The aim of this study was to clarify the clinical, laboratory, and imaging findings of ovarian cancer in association with endometriotic cysts by detailed comparison of the findings of benign and malignant tumors.
This was a retrospective study of 138 women who had an operation for ovarian tumors at the Department of Obstetrics and Gynecology of Kochi Health Sciences Center between September 1, 2011, and July 30, 2015. The ovarian tumors were divided into two groups: the benign group (endometriotic cysts) and the malignant group (ovarian cancer in association with endometriotic cysts).
Of the 138 patients, 28 had malignant disease, and 110 had benign endometriotic cysts. Patients in the malignant group were significantly older than patients in the benign group. The mean maximum tumor diameter was also significantly larger for the malignant tumors. Unilocular-solid and multilocular-solid type tumors were present in 25.0% and 75.0% of malignant tumors, and in 9.1% and 19.1% of benign tumors, respectively. The mean maximum solid component diameter and height were significantly larger in the malignant tumors than in the benign tumors. The solid components were present on the abdominal side of the cyst wall in 12.5% of benign tumors and in 51.9% of malignant tumors.
In elderly patients, the presence of large solid components in large endometriotic cysts, especially the abdominal side of the cyst wall, might suggest malignancy.
The aim of this study was to clarify the findings of ovarian cancer in association with endometriotic cysts by detailed comparison of the findings of benign and malignant tumors. The presence of solid components in large endometriotic cysts, especially the abdominal side of the cyst wall, might suggest malignancy.
本研究旨在通过详细比较良性和恶性肿瘤的表现，阐明与子宫内膜异位囊肿相关的卵巢癌的临床、实验室及影像学表现。
这是一项对138例在高知健康科学中心妇产科接受卵巢肿瘤手术的女性进行的回顾性研究。这些卵巢肿瘤被分为两组：良性组（子宫内膜异位囊肿）和恶性组（与子宫内膜异位囊肿相关的卵巢癌）。
138例患者中，28例患有恶性疾病，110例患有良性子宫内膜异位囊肿。恶性组患者的年龄显著大于良性组患者。恶性肿瘤的平均最大肿瘤直径也显著更大。单房实性和多房实性类型的肿瘤在恶性肿瘤中分别占25.0%和75.0%，在良性肿瘤中分别占9.1%和19.1%。恶性肿瘤的平均最大实性成分直径和高度显著大于良性肿瘤。实性成分出现在良性肿瘤囊肿壁腹侧的占12.5%，出现在恶性肿瘤囊肿壁腹侧的占51.9%。
在老年患者中，大的子宫内膜异位囊肿中存在大的实性成分，尤其是囊肿壁的腹侧，可能提示恶性。
本研究旨在通过详细比较良性和恶性肿瘤的表现，阐明与子宫内膜异位囊肿相关的卵巢癌的表现。大的子宫内膜异位囊肿中存在实性成分，尤其是囊肿壁的腹侧，可能提示恶性。
