Jessop Fertility, Jessop Wing, Sheffield Teaching Hospitals NHS Foundation Trust, Tree Root Walk, Sheffield, S10 2SF, UK.
Best Pract Res Clin Obstet Gynaecol. 2018 Nov;53:30-37. doi: 10.1016/j.bpobgyn.2018.07.001. Epub 2018 Jul 31.
There is a global recognition of the need to reduce multiple pregnancies following assisted reproductive technology. Complications of multiple pregnancies can be simply avoided by replacing one embryo at a time. Most policies to reduce the number of double or higher order embryo transfers involve predicting which patients are at most risk by using a multiple birth minimisation strategy. These frequently consider factors such as patient age, previous treatments and embryo quality. However, with improvements in methods of embryo culture, embryo selection and cryopreservation, this chapter will question whether, at present, it is time to move to single embryo transfer (SET) for all.
人们普遍认识到,需要减少辅助生殖技术后的多胎妊娠。通过每次移植一个胚胎,可以简单地避免多胎妊娠的并发症。大多数减少双胎或多胎胚胎移植数量的政策都涉及到通过采用减少多胎妊娠策略来预测哪些患者风险最大。这些策略通常会考虑患者年龄、以往治疗和胚胎质量等因素。然而,随着胚胎培养、胚胎选择和冷冻保存方法的改进,本章将质疑目前是否应该为所有患者都采用单胚胎移植(SET)。