纤维蛋白胶胸腔粘连术治疗极早产儿气胸：病例报告及文献复习。
Fibrin glue pleurodesis for pneumothorax in extremely preterm infants: a case report and literature review.
机构信息
Division of Neonatology, Careggi University Hospital of Florence, Largo Brambilla 3, 50141, Florence, Italy.
Department of Neurosciences, Psychology, Drug Research and Child Health, Careggi University Hospital of Florence, Florence, Italy.
出版信息
Ital J Pediatr. 2018 Aug 14;44(1):91. doi: 10.1186/s13052-018-0533-6.
BACKGROUND
Chest tube drainage and mechanical ventilation are effective treatment of symptomatic pneumothorax (PTX), but the best management of persistent (> 7 days) PTX is unknown.
CASE PRESENTATION
We reported a case of successful fibrin glue pleurodesis of persistent PTX in an extremely preterm infant without adverse effects. We discussed previous literature on this treatment.
CONCLUSIONS
Overall, the twelve reported cases suggest that persistent PTX sealing with fibrin glue can represent a simple, quick, and effective treatment whose possible reported adverse effects are transient and do not cause permanent sequelae. Thus, fibrin glue pleurodesis might be considered a suitable therapeutic tool in very preterm infant with persistent PTX.
背景
胸腔引流管和机械通气是治疗症状性气胸（PTX）的有效方法，但持续性（>7 天）PTX 的最佳治疗方法尚不清楚。
病例介绍
我们报告了一例极低出生体重儿持续性气胸成功行纤维蛋白胶胸膜固定术的病例，且无不良反应。我们对该治疗方法的既往文献进行了讨论。
结论
总体而言，十二例报告的病例表明，纤维蛋白胶可有效、快速、简便地治疗持续性气胸，且可能出现的不良反应为一过性，不会导致永久性后遗症。因此，纤维蛋白胶胸膜固定术可能是治疗持续性气胸的非常早产儿的一种合适的治疗手段。
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