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Treatment of AL amyloidosis with bendamustine: a study of 122 patients.

作者信息

Milani Paolo, Schönland Stefan, Merlini Giampaolo, Kimmich Christoph, Foli Andrea, Dittrich Tobias, Basset Marco, Müller-Tidow Carsten, Bochtler Tilmann, Palladini Giovanni, Hegenbart Ute

机构信息

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Department of Molecular Medicine, University of Pavia, Pavia, Italy; and.

出版信息

Blood. 2018 Nov 1;132(18):1988-1991. doi: 10.1182/blood-2018-04-845396. Epub 2018 Aug 14.

DOI:10.1182/blood-2018-04-845396
PMID:30108065
Abstract
摘要

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Treatment of AL amyloidosis with bendamustine: a study of 122 patients.苯达莫司汀治疗AL淀粉样变性:122例患者的研究
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Response to bendamustine is associated with a survival advantage in a heavily pretreated patients with AL amyloidosis.对于接受过大量预处理的 AL 淀粉样变性患者,苯达莫司汀治疗反应与生存优势相关。
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Updated analysis of phase 2 study of bendamustine and dexamethasone in patients with relapsed/refractory systemic light chain (AL) amyloidosis.苯达莫司汀与地塞米松治疗复发/难治性系统性轻链(AL)淀粉样变性患者的2期研究的更新分析。
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A good clonal response to chemotherapy in AL amyloidosis is associated with improved quality of life and function at 1 year.在AL淀粉样变性中,对化疗产生良好的克隆反应与1年后生活质量和功能的改善相关。
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A Focus on Waldenström Macroglobulinemia and AL Amyloidosis.聚焦华氏巨球蛋白血症和AL型淀粉样变性。
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J Blood Med. 2019 Oct 23;10:373-380. doi: 10.2147/JBM.S183857. eCollection 2019.