Bostwick J, Paletta C, Hartrampf C R
Ann Surg. 1986 May;203(5):481-90. doi: 10.1097/00000658-198605000-00006.
Women who select conservative treatment for carcinoma of the breast (tumor excision followed by supervoltage radiation therapy) place a premium on breast preservation and aesthetics. When local control fails and they require a mastectomy, or when the aesthetic appearance is unacceptable, they may request breast reconstruction. The goal of this study is to evaluate a series of 10 patients who required reconstructive breast surgery after complications of conservative treatment. Patient classification: I. Breast or chest wall necrosis (3). II. Breast fibrosis and gross asymmetry (3). III. Local recurrence of breast cancer (5). IV. Positive margins after the initial lumpectomy (1). The mean age was 34 years. Radiation dosage average was 5252 rads with two patients receiving iridium-192 implant boosts. The reconstructive management was complex and usually required a major musculocutaneous flap because of the radiation effects.
选择乳腺癌保守治疗（肿瘤切除后行超高压放射治疗）的女性非常重视乳房保留和美观。当局部控制失败且需要进行乳房切除时，或者当美学外观不可接受时，她们可能会要求进行乳房重建。本研究的目的是评估一系列10例在保守治疗出现并发症后需要进行乳房重建手术的患者。患者分类：I. 乳房或胸壁坏死（3例）。II. 乳房纤维化和严重不对称（3例）。III. 乳腺癌局部复发（5例）。IV. 初次肿块切除术后切缘阳性（1例）。平均年龄为34岁。平均放射剂量为5252拉德，两名患者接受了铱-192植入物增强放疗。由于放疗的影响，重建管理很复杂，通常需要一个大型肌皮瓣。
