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Pityriasis rubra pilaris-like erythroderma in the setting of pembrolizumab therapy responsive to acitretin.

作者信息

Coleman Emily, Panse Gauri, Haldas Jason, Gettinger Scott N, Leventhal Jonathan S

机构信息

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

出版信息

JAAD Case Rep. 2018 Aug 9;4(7):669-671. doi: 10.1016/j.jdcr.2018.06.022. eCollection 2018 Aug.

DOI:10.1016/j.jdcr.2018.06.022
PMID:30112450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6091308/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd71/6091308/00d103e720d9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd71/6091308/bf8251e9b132/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd71/6091308/00d103e720d9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd71/6091308/bf8251e9b132/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd71/6091308/00d103e720d9/gr2.jpg

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JAMA Dermatol. 2017 Apr 1;153(4):304-308. doi: 10.1001/jamadermatol.2016.5384.
2
Diverse types of dermatologic toxicities from immune checkpoint blockade therapy.免疫检查点阻断疗法引发的多种类型皮肤毒性反应。
J Cutan Pathol. 2017 Feb;44(2):158-176. doi: 10.1111/cup.12858. Epub 2016 Dec 21.
3
Anti-PD1-induced psoriasis: a study of 21 patients.抗程序性死亡蛋白1(Anti-PD1)诱导的银屑病:21例患者的研究
J Dtsch Dermatol Ges. 2021 Nov;19(11):1621-1643. doi: 10.1111/ddg.14641.
4
The Clinical and Histopathological Features of Cutaneous Immune-Related Adverse Events and Their Outcomes.皮肤免疫相关不良事件的临床和组织病理学特征及其结局
J Clin Med. 2021 Feb 12;10(4):728. doi: 10.3390/jcm10040728.
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Inflammatory eruptions associated with immune checkpoint inhibitor therapy: A single-institution retrospective analysis with stratification of reactions by toxicity and implications for management.免疫检查点抑制剂治疗相关炎症性皮疹:毒性分层的单机构回顾性分析及其对治疗的影响。
J Am Acad Dermatol. 2019 Apr;80(4):990-997. doi: 10.1016/j.jaad.2018.10.062. Epub 2018 Nov 3.
J Eur Acad Dermatol Venereol. 2017 May;31(5):e254-e257. doi: 10.1111/jdv.14011. Epub 2016 Nov 7.
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Pityriasis lichenoides chronica-like drug eruption developing during pembrolizumab treatment for metastatic melanoma.在帕博利珠单抗治疗转移性黑色素瘤期间发生的慢性苔藓样糠疹样药物疹。
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PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.PD-1 阻断增强了前列腺癌和晚期黑色素瘤患者外周血中的 Th1 和 Th17,抑制了 Th2 反应。
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