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振动钻孔对骨坏死的参数效应及与皮质骨传统钻孔的比较组织病理学研究

Parametric effect of vibrational drilling on osteonecrosis and comparative histopathology study with conventional drilling of cortical bone.

作者信息

Singh Gurmeet, Jain Vivek, Gupta Dheeraj, Sharma Abhimanyu

机构信息

1 Mechanical Engineering Department, Thapar Institute of Engineering & Technology (Deemed to be University), Patiala, India.

2 Department of Pathology, Maharishi Markandeshwar Institute of Medical Sciences & Research (Deemed to be University), Mullana, Ambala, India.

出版信息

Proc Inst Mech Eng H. 2018 Oct;232(10):975-986. doi: 10.1177/0954411918794983. Epub 2018 Aug 16.

DOI:10.1177/0954411918794983
PMID:30112958
Abstract

Drilling to the bones is required to re-fix them at their appropriate location using the implants. During drilling some thermal and mechanical losses may be faced by the bone and surrounding tissues which may lead to the serious issue in terms of osteonecrosis. Osteonecrosis is one of the reasons for impaired healing process for the fractured bone and causes further complications like low pullout strength of cortical screws and bone crush. In order to maintain the low temperature during bone drilling, this study focused the thermal damages observed by the bone and its surrounding during bone drilling and compared the results of conventional and vibrational drilling techniques. Parametric optimization under the influence of vibrations was also studied. Drilling has been done with the both drilling technique, and results were recorded in terms of temperature raise. Optimal solution for drilling the bone has been accessed using Taguchi optimization technique. The morphological comparison has been done for conventional and vibrational drilled holes using histopathology of drilled bones sections. From Taguchi optimization, it was observed that R1F1A1 is the parametric combination which gives minimum thermal injury to the bone in case of vibrational bone drilling. Analysis of variance cleared that the all parameters involved significantly affect the results (P ≤ 0.05). Rotational speed was found to be the most influential factor among the all with 80.53%. Histopathology studies of bone specimens help to understand how heat generation affects the bone morphology during drilling. The specimens drilled with vibrational drilling show less damage in terms of osteonecrosis near the drill site which shows the significance of vibrational drilling in case of orthopedic surgeries. The raise in temperature during drilling is collective result of different drilling parameters. Vibrational drilling was observed a helping tool to control the thermal damage in bone drilling.

摘要

需要钻孔至骨骼,以便使用植入物将其重新固定在适当位置。在钻孔过程中,骨骼和周围组织可能会面临一些热损失和机械损失,这可能会导致骨坏死这一严重问题。骨坏死是骨折愈合过程受损的原因之一,会引发进一步的并发症,如皮质螺钉拔出力低和骨挤压。为了在骨钻孔过程中保持低温,本研究聚焦于骨钻孔过程中骨骼及其周围观察到的热损伤,并比较了传统钻孔技术和振动钻孔技术的结果。还研究了振动影响下的参数优化。使用这两种钻孔技术进行了钻孔,并记录了温度升高的结果。使用田口优化技术获得了骨钻孔的最佳解决方案。使用钻孔骨骼切片的组织病理学对传统钻孔和振动钻孔的孔进行了形态学比较。从田口优化中可以观察到,R1F1A1是振动骨钻孔情况下对骨骼热损伤最小的参数组合。方差分析表明,所有涉及的参数均对结果有显著影响(P≤0.05)。发现转速在所有参数中影响最大,为80.53%。骨标本的组织病理学研究有助于了解钻孔过程中热量产生如何影响骨形态。振动钻孔的标本在钻孔部位附近的骨坏死方面显示出较少的损伤,这表明振动钻孔在骨科手术中的重要性。钻孔过程中的温度升高是不同钻孔参数的综合结果。振动钻孔被认为是控制骨钻孔热损伤的一种辅助工具。

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