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ESMO 睾丸生殖细胞癌共识会议:诊断、治疗和随访。

ESMO Consensus Conference on testicular germ cell cancer: diagnosis, treatment and follow-up.

机构信息

Tumor and Breast Center ZeTuP, St. Gallen, Switzerland; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumorzentrum, University Medical Center, Hamburg, Germany.

Department of Medical Oncology, Hospital Universitari i Politècnic la Fe, Valencia, Spain.

出版信息

Ann Oncol. 2018 Aug 1;29(8):1658-1686. doi: 10.1093/annonc/mdy217.

Abstract

The European Society for Medical Oncology (ESMO) consensus conference on testicular cancer was held on 3-5 November 2016 in Paris, France. The conference included a multidisciplinary panel of 36 leading experts in the diagnosis and treatment of testicular cancer (34 panel members attended the conference; an additional two panel members [CB and K-PD] participated in all preparatory work and subsequent manuscript development). The aim of the conference was to develop detailed recommendations on topics relating to testicular cancer that are not covered in detail in the current ESMO Clinical Practice Guidelines (CPGs) and where the available level of evidence is insufficient. The main topics identified for discussion related to: (1) diagnostic work-up and patient assessment; (2) stage I disease; (3) stage II-III disease; (4) post-chemotherapy surgery, salvage chemotherapy, salvage and desperation surgery and special topics; and (5) survivorship and follow-up schemes. The experts addressed questions relating to one of the five topics within five working groups. Relevant scientific literature was reviewed in advance. Recommendations were developed by the working groups and then presented to the entire panel. A consensus vote was obtained following whole-panel discussions, and the consensus recommendations were then further developed in post-meeting discussions in written form. This manuscript presents the results of the expert panel discussions, including the consensus recommendations and a summary of evidence supporting each recommendation. All participants approved the final manuscript.

摘要

欧洲肿瘤内科学会(ESMO)睾丸癌共识会议于 2016 年 11 月 3 日至 5 日在法国巴黎举行。会议包括一个由 36 名在睾丸癌诊断和治疗方面的领先专家组成的多学科小组(34 名小组成员出席了会议;另外两名小组成员[CB 和 K-PD]参加了所有的筹备工作和随后的手稿开发)。会议的目的是制定与睾丸癌相关的详细建议,这些建议在当前 ESMO 临床实践指南(CPGs)中没有详细涵盖,而且可用的证据水平不足。确定的主要讨论主题包括:(1)诊断工作和患者评估;(2)I 期疾病;(3)II-III 期疾病;(4)化疗后手术、挽救性化疗、挽救性和绝望性手术和特殊主题;以及(5)生存和随访方案。专家们在五个工作组中讨论了与其中一个主题相关的问题。事先审查了相关的科学文献。建议由工作组制定,然后提交给全体小组成员。在全体小组成员讨论后进行了共识投票,并在会后以书面形式进一步制定了共识建议。本文档介绍了专家小组讨论的结果,包括共识建议和支持每项建议的证据摘要。所有与会者都批准了最终的手稿。

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