Monte A F G, Reis A F, Cruz Junior L B, Antunes A
Appl Opt. 2018 Jul 10;57(20):5865-5871. doi: 10.1364/AO.57.005865.
We described a method for the preparation of polydimethylsiloxane (PDMS) phantoms to mimic the optical properties of biologic tissues at distinct wavelengths ranging from the visible to the near-infrared spectra. The present method for fabricating solid optical tissue phantoms using zinc-phthalocyanine chromophores has demonstrated high photostability with optical absorption coefficients up to 1.0 mm, making this phantom proper with absorption bands ranging from 600 to 850 nm. It also happens that the chromophore absorption coefficient is linear as a function of its concentration inside the previous optical window. The optical scattering properties were quantitatively selected by adding TiO particle concentrations to the PDMS phantom. Thus, the quantitative optical properties of absorption and scattering for a large-batch fabrication were demonstrated, making the zinc-phthalocyanine phantoms suitable for use as a reference standard.
我们描述了一种制备聚二甲基硅氧烷（PDMS）体模的方法，以模拟生物组织在从可见光到近红外光谱的不同波长下的光学特性。目前使用锌酞菁发色团制造固体光学组织体模的方法已证明具有高光稳定性，光吸收系数高达1.0 mm，使得该体模适用于600至850 nm的吸收带。还发现，在先前的光学窗口内，发色团吸收系数与其浓度呈线性关系。通过向PDMS体模中添加TiO颗粒浓度来定量选择光学散射特性。因此，展示了用于大批量制造的吸收和散射的定量光学特性，使得锌酞菁体模适合用作参考标准。
