关注声明：2型白细胞介素-1受体（IL1R2）的短发夹RNA（shRNA）抑制人骨肉瘤U-2 OS细胞的增殖。 - Suppr

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超能文献

Expression of concern: Short hairpin RNA (shRNA) of type 2 interleukin-1 receptor (IL1R2) inhibits the proliferation of human osteosarcoma U-2 OS cells.

作者信息

Liu Xiwei, Min Li, Duan Hong, Shi Rui, Zhang Wenli, Hong Song, Tu Chongqi

机构信息

Department of Orthopedics, West China Hospital, Sichuan University, Guoxue Xiang 37#, Chengdu, 610041, China.

出版信息

Med Oncol. 2018 Aug 17;35(10):129. doi: 10.1007/s12032-018-1177-5.

DOI:10.1007/s12032-018-1177-5

PMID:30120568

Abstract

摘要

相似文献

Expression of concern: Short hairpin RNA (shRNA) of type 2 interleukin-1 receptor (IL1R2) inhibits the proliferation of human osteosarcoma U-2 OS cells.关注声明：2型白细胞介素-1受体（IL1R2）的短发夹RNA（shRNA）抑制人骨肉瘤U-2 OS细胞的增殖。

Med Oncol. 2018 Aug 17;35(10):129. doi: 10.1007/s12032-018-1177-5.

Short hairpin RNA (shRNA) of type 2 interleukin-1 receptor (IL1R2) inhibits the proliferation of human osteosarcoma U-2 OS cells.2型白细胞介素-1受体（IL1R2）的短发夹RNA（shRNA）抑制人骨肉瘤U-2 OS细胞的增殖。

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May Be Involved in Progression of Osteosarcoma by Regulating miR-124-3p-, miR-27a-3p-, and miR-103/590-3p- Axes.可能通过调节 miR-124-3p、miR-27a-3p 和 miR-103/590-3p 轴来参与骨肉瘤的进展。

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Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I receptor.人骨肉瘤（U-2 OS）细胞同时表达胰岛素样生长因子-I（IGF-I）受体和胰岛素样生长因子-II/甘露糖-6-磷酸（IGF-II/M6P）受体，并合成IGF-II：IGF-II通过IGF-I受体进行自分泌生长刺激。

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Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells inhibits cell proliferation by inducing cell cycle arrest in the G0/G1 phase.慢病毒介导的 shRNA 敲低人骨肉瘤细胞中的 MED19 通过诱导 G0/G1 期细胞周期阻滞抑制细胞增殖。

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shRNA-mediated silencing of hTERT suppresses proliferation and promotes apoptosis in osteosarcoma cells.shRNA 介导的 hTERT 沉默抑制骨肉瘤细胞的增殖并促进其凋亡。

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本文引用的文献

Med Oncol. 2015 Jan;32(1):364. doi: 10.1007/s12032-014-0364-2. Epub 2014 Nov 29.

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