[波多黎各艾滋病病毒/艾滋病确诊患者的生存分析]
[Survival analysis in people diagnosed with HIV/AIDS in Puerto Rico].
作者信息
Marzán-Rodríguez Melissa, Zavala Segarra Diego E, Valverde Juan Carlas Orengo, Varas-Díaz Nelson, De León Sandra Miranda, Acevedo-Díaz Eliseo
机构信息
Es Investigadora Post-Doctoral en el Centro de Investigación y Evaluación Sociomédica del Recinto de Ciencias Médicas de la Universidad de Puerto Rico. Profesora Asistente en Epidemiología del Programa de Salud Pública de la Ponce Health Sciences University
Es Director del Registro de Cáncer de Puerto Rico, Co-InvestigadorPrincipal del Sistema de Muertes Violentas de Puerto adscrito al Instituto de Estadística de Puerto Rico y Profesoren Epidemiología del Programa de Salud Pública de la Ponce Health Sciences University.
出版信息
Rev Puertoriq Med Salud Publica. 2018;66:8-14.
After the introduction of HAART, the HIV/AIDS epidemiological trends has shown an increasing in the survival rates. HAART has dramatically improved the life expectancy of HIV/AIDS. The objective of this study was to estimate survival in people diagnosed with HIV/AIDS in Puerto Rico (PR) from 2003-2011. A population-based study using the PR HIV Surveillance System was implemented. A total of N = 9,290 people were diagnosed with HIV/AIDS in PR for 2003-2011 period. Cox regression models for survival analysis were assessed. Survival at 6 years after diagnosis in HIV patients was 0.87 (CI95%: 0.09, 0.72) when compare with AIDS patients at same time of diagnosis was 0.57 (CI95%: 0.55, 0.60) p<0.001. Intravenous drug users [IDU] have less probability of survival at 5 years after diagnosis when compare with other transmission modes 0.69 (CI95%: 0.67, 0.71) p<0.001. Assertive prevention strategies must be developed and implemented in PR for IDU's in order to increase their survival rates.
高效抗逆转录病毒治疗（HAART）引入后，艾滋病毒/艾滋病的流行病学趋势显示存活率有所上升。HAART显著提高了艾滋病毒/艾滋病患者的预期寿命。本研究的目的是估计2003年至2011年期间在波多黎各（PR）被诊断为艾滋病毒/艾滋病的患者的生存率。采用PR艾滋病毒监测系统开展了一项基于人群的研究。在2003 - 2011年期间，PR共有N = 9290人被诊断为艾滋病毒/艾滋病。评估了用于生存分析的Cox回归模型。艾滋病毒患者诊断后6年的生存率为0.87（95%置信区间：0.09，0.72），而同期艾滋病患者的生存率为0.57（95%置信区间：0.55，0.60），p<0.001。与其他传播方式相比，静脉吸毒者（IDU）在诊断后5年的生存概率较低，为0.69（95%置信区间：0.67，0.71），p<0.001。为了提高波多黎各IDU的生存率，必须制定并实施积极的预防策略。
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