Bacteremia due to Staphylococcus aureus - the importance of appropriate management.

Staphylococcus aureus bacteremia (SAB) is the most common cause of severe bloodstream infections with high incidence and lethality. The diagnosis of SAB must be followed by an appropriate diagnostic and therapeutic management. The aim of the study was to identify clinical and epidemiological characteristics of SAB cases treated in the Central Military Hospital Prague and to assess compliance with the guidelines for diagnosis and thera-py. A total of 65 patients with S. aureus blood culture positivity were enrolled in the retrospective study. Sixty SAB cases (92%) were caused by MSSA strains, and MRSA strains were detected in five patients (8%). The source of the infection was confirmed in 83% of patients. The average case fatality rate in the study cohort was 28%. The analysis of the quality of care suggested both diagnostic and therapeutic insufficiencies in 65% of SAB patients. Overall, the result of the study supports the importance of the role of infectious disease specialists played in the bedside management of patients with SAB.