Liang Chengmin, Zhang Wei, Liu Bin, Yu Haiyang, Cao Jie, Yin Wen
Spine and Trauma Ward, Department of Orthopedics, Fuyang People's Hospital, Fuyang Clinical College of Anhui Medical University, Fuyang Anhui, 236000, P.R.China.
Spine and Trauma Ward, Department of Orthopedics, Fuyang People's Hospital, Fuyang Clinical College of Anhui Medical University, Fuyang Anhui, 236000,
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Jul 15;32(7):920-926. doi: 10.7507/1002-1892.201801160.
To discuss the security and effectiveness of fixing the unstable region of sagittal injured unit symmetrically with pedicle screws combined with bone graft fusion for treating thoracolumbar fractures.
A series of 65 patients with a single level thoracolumbar fracture between November 2011 and November 2015 were included in the study. There were 41 males and 24 females with an average age of 36.7 years (range, 23-60 years). The fracture segments included T 1 case, T in 2 cases, T in 4 cases, T in 8 cases, T in 14 cases, L in 19 cases, L in 13 cases, L in 3 cases, and L in 1 case. According to AO classification, there were 34 cases classified as type A, 27 cases type B, and 4 cases type C. The neurological function was evaluated by American Spinal Injury Association (ASIA) grade score, there were 1 case at grade A, 2 cases grade B, 6 cases grade C, 15 cases grade D, and 41 cases grade E. The thoracolumbar injury severity score (TLICS) was 4 in 9 cases, 5 in 29 cases, 6-8 in 23 cases, 9-10 in 4 cases. The time form injury to operation was 2-12 days (mean, 5.3 days). The fractured vertebra, along with the superior and inferior discs were defined as a injured unit and divided into three parts on the sagittal position: region Ⅰ mainly including the superior disc, cephalic 1/3 of injured vertebra, and posterior ligamentous complex as to oppose; region Ⅱ mainly including the middle 1/3 of injured vertebra, pedicles, lamina, spinous process, and supraspinal ligament; region Ⅲ mainly including the inferior disc, caudal 1/3 of injured vertebra, and posterior ligamentous complex as to oppose. The unstable region was defined as the key injured region of the vertebra. Pedicle screws were fixed symmetrically and correspondingly with bone grafting to treat thoracolumbar fractures. The neurological status, ratio of anterior body height, and sagittal Cobb angle were collected at preoperation, immediate after operation, and last follow-up to evaluate surgical and clinical outcomes.
All patients accepted operation safely and were followed up 12-24 months (mean, 17.3 months). Cerebrospinal fluid leakage occurred in 3 patients, and cured by symptomatic treatment. There was no complications such as loosening, displacement, and breakage of internal fixator. Bony fusion was achieved in all patients at 10-13 months (mean, 11.4 months) after operation. At last follow-up, according to ASIA grading, 1 case was grade A, 1 grade B, 3 grade C, 9 grade D, and 51 grade E, showing significant difference when compared with preoperative data ( =-2.963, =0.014). The ratio of anterior body height at preoperation, immediate after operation, and last follow-up were 53.2%±6.8%, 91.3%±8.3%, 89.5%±6.6% respectively; and the sagittal Cobb angle were (16.3±8.1), (2.6±7.5), (3.2±6.8)° respectively. The ratio of anterior body height and the sagittal Cobb angle at immediate after operation and at last follow-up were significantly improved when compared with preoperative values ( <0.05), but no significant difference was found between at immediate after operation and at last follow-up ( >0.05).
It is safe and reliable to treat thoracolumbar fractures under the principle of fixing the unstable region of injured unit symmetrically with pedicle screws combined with bone grafting.
探讨经椎弓根螺钉对称固定矢状位损伤单元不稳定区并结合植骨融合治疗胸腰椎骨折的安全性及有效性。
纳入2011年11月至2015年11月间65例单节段胸腰椎骨折患者。其中男性41例,女性24例,平均年龄36.7岁(范围23 - 60岁)。骨折节段包括T1 1例、T2 2例、T3 4例、T4 8例、T5 14例、L1 19例、L2 13例、L3 3例、L4 1例。按AO分类,A型34例,B型27例,C型4例。采用美国脊髓损伤协会(ASIA)分级评分评估神经功能,A级1例,B级2例,C级6例,D级15例,E级41例。胸腰椎损伤严重程度评分(TLICS):4分9例,5分29例,6 - 8分23例,9 - 10分4例。受伤至手术时间为2 - 12天(平均5.3天)。将骨折椎体及其上下椎间盘定义为一个损伤单元,在矢状位上分为三个部分:Ⅰ区主要包括上椎间盘、损伤椎体的头侧1/3及相对的后韧带复合体;Ⅱ区主要包括损伤椎体的中1/3、椎弓根、椎板、棘突及棘上韧带;Ⅲ区主要包括下椎间盘、损伤椎体的尾侧1/3及相对的后韧带复合体。不稳定区定义为椎体的关键损伤区域。采用椎弓根螺钉对称、相应固定并结合植骨治疗胸腰椎骨折。收集术前、术后即刻及末次随访时的神经功能状态、椎体前缘高度比值及矢状位Cobb角,评估手术及临床疗效。
所有患者手术均顺利,随访12 - 24个月(平均17.3个月)。3例患者出现脑脊液漏,经对症治疗治愈。未出现内固定松动、移位及断裂等并发症。所有患者术后10 - 13个月(平均11.4个月)实现骨性融合。末次随访时,按ASIA分级,A级1例,B级1例,C级3例,D级9例,E级51例,与术前数据比较差异有统计学意义(Z = -2.963,P = 0.014)。术前、术后即刻及末次随访时椎体前缘高度比值分别为53.2%±6.8%、91.3%±8.3%、89.5%±6.6%;矢状位Cobb角分别为(16.3±8.1)°、(2.6±7.5)°、(3.2±6.8)°。术后即刻及末次随访时椎体前缘高度比值及矢状位Cobb角与术前比较均显著改善(P < 0.05),但术后即刻与末次随访比较差异无统计学意义(P > 0.05)。
遵循经椎弓根螺钉对称固定损伤单元不稳定区并结合植骨的原则治疗胸腰椎骨折安全可靠。