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一种严重且广泛的动脉粥样硬化栓塞性疾病的非典型表现。

An atypical presentation of a severe and massive atheroembolic disease.

作者信息

Falcão Luis Pedro, Fernandes Sara, Costa Ana Cortesão, Teixeira Catarina, Raimundo Mário, Silva Sónia, Miranda Margarida, Almeida Edgar De

机构信息

Hospital Beatriz Ângelo, Departamento de Nefrologia, Loures, Portugal.

Hospital Beatriz Ângelo, Departamento de Oftalmologia, Loures, Portugal.

出版信息

J Bras Nefrol. 2019 Jan-Mar;41(1):142-144. doi: 10.1590/2175-8239-JBN-2018-0013. Epub 2018 Aug 20.

DOI:10.1590/2175-8239-JBN-2018-0013
PMID:30129967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6534016/
Abstract

Atheroembolic renal disease (AERD) is a kidney manifestation of atherosclerosis as a systemic disease. AERD is defined as a renal impairment secondary to embolization of cholesterol crystals with consequent occlusion of renal vascularization. The current case report describes one patient with multiple risk factors but without any inciting event history who presents a very atypical clinical course of a severe and massive atheroembolic disease that developed spontaneously and silently.

摘要

动脉粥样硬化栓塞性肾病（AERD）是作为一种全身性疾病的动脉粥样硬化的肾脏表现。AERD被定义为继发于胆固醇结晶栓塞并导致肾血管阻塞的肾功能损害。本病例报告描述了一名具有多种危险因素但无任何诱发事件病史的患者，该患者呈现出一种非常不典型的临床病程，即严重且广泛的动脉粥样硬化栓塞性疾病自发且隐匿地发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/6145c3fe1293/2175-8239-jbn-2018-0013-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/da894c30bacf/2175-8239-jbn-2018-0013-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/3dc84e8dc0b5/2175-8239-jbn-2018-0013-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/6145c3fe1293/2175-8239-jbn-2018-0013-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/da894c30bacf/2175-8239-jbn-2018-0013-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/3dc84e8dc0b5/2175-8239-jbn-2018-0013-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eab/6534016/6145c3fe1293/2175-8239-jbn-2018-0013-gf03.jpg

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本文引用的文献

1
The challenge of diagnosing atheroembolic renal disease clinical features and prognostic factors. Circulation 116: 298-304, 2007.动脉粥样硬化栓塞性肾病的诊断挑战：临床特征与预后因素。《循环》116: 298 - 304, 2007年。
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Cholesterol embolization syndrome.胆固醇栓塞综合征。
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3
Atheroembolic renal disease.动脉粥样栓塞性肾病。
Lancet. 2010 May 8;375(9726):1650-60. doi: 10.1016/S0140-6736(09)62073-0. Epub 2010 Apr 8.
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Cholesterol crystal embolism: diagnosis and treatment.胆固醇结晶栓塞：诊断与治疗
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Atheromatous embolization.动脉粥样硬化栓塞
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Predictors of renal and patient outcomes in atheroembolic renal disease: a prospective study.
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Treatment of atheroembolization with corticosteroids.用皮质类固醇治疗动脉粥样硬化栓塞。
Am J Hypertens. 2001 Aug;14(8 Pt 1):831-4. doi: 10.1016/s0895-7061(01)02183-5.
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Atheroembolic renal disease.动脉粥样硬化栓塞性肾病
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9
Cholesterol crystal embolism: A recognizable cause of renal disease.胆固醇结晶栓塞：一种可识别的肾脏疾病病因。
Am J Kidney Dis. 2000 Dec;36(6):1089-109. doi: 10.1053/ajkd.2000.19809.
10
A possible role of corticosteroids in cholesterol crystal embolization.皮质类固醇在胆固醇结晶栓塞中的可能作用。
Nephron. 1999;83(2):189-90. doi: 10.1159/000045509.