Wolkin A, Jordan B, Peselow E, Rubinstein M, Rotrosen J
Am J Psychiatry. 1986 Jul;143(7):912-4. doi: 10.1176/ajp.143.7.912.
Preclinical and clinical observations suggest that enhancement of prostaglandin activity inhibits catecholamine release and may have antidyskinetic effects. A double-blind therapeutic trial with prostaglandin precursor essential fatty acids was conducted in 16 patients with tardive dyskinesia. No beneficial effects were seen.
临床前和临床观察表明,前列腺素活性增强可抑制儿茶酚胺释放,并可能具有抗运动障碍作用。对16例迟发性运动障碍患者进行了一项使用前列腺素前体必需脂肪酸的双盲治疗试验。未观察到有益效果。