Department of General Surgery and Therapy Center for Peritoneal Carcinomatosis, Marien Hospital Herne, Ruhr-Universität Bochum, Herne, Germany.
Basic Research Laboratories, Department of Surgery, Marien Hospital Herne, Ruhr-Universität Bochum, Herne, Germany.
J Gastrointest Surg. 2018 Dec;22(12):2187-2193. doi: 10.1007/s11605-018-3916-5. Epub 2018 Aug 21.
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new approach to deliver intraperitoneal chemotherapy as a pressurized aerosol in patients with advanced peritoneal metastases (PM). Although this treatment has rapidly been adopted into clinical practice, most surgeons are not familiar with the basics and principles of this technology. The purpose of this article is to review patient selection criteria, as well as highlighting important operative and technical details regarding PIPAC technology with a focus on "how to do it." To this end, safety and feasibility data from a series of 1200 consecutive PIPAC procedures performed by two pioneers of PIPAC treatment are presented.
腹腔内压力气溶胶化疗（PIPAC）是一种将腹腔内化疗作为加压气溶胶输送给晚期腹膜转移（PM）患者的新方法。尽管这种治疗方法已迅速被应用于临床实践，但大多数外科医生并不熟悉该技术的基础知识和原理。本文的目的是回顾患者选择标准，并强调 PIPAC 技术的重要手术和技术细节，重点是“如何做到这一点”。为此，介绍了两位 PIPAC 治疗先驱进行的 1200 例连续 PIPAC 手术的一系列安全性和可行性数据。
