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结核菌素敏感性的被动转移(作者译)

[Passive transfer of tuberculin sensitivity (author's transl)].

作者信息

Kohout P

出版信息

Wien Klin Wochenschr. 1977 May 13;89(10):333-6.

PMID:301327
Abstract

Tuberculin sensitivity can be transfered passively by cells. The active principle may be bound on T-lymphocytes. In patients with sarcoidosis or with malignant lymphadenomas, the passive transfer of tuberculin sensitivity via lymphocytes of tuberculin-positive donors is more difficult. In sarcoidosis the achievement of a positive tuberculin reaction at an appreciable distance from the site of transfer was possible only with markedly greater amounts of donor lymphocytes than in healthy controls. In patients with malignant lymphadenomas such a transfer succeeded only very rarely. The qualitative and quantitative differences in the impairment of the delayed immune sensitivity in both groups and their possible causes are discussed.

摘要

结核菌素敏感性可通过细胞被动转移。活性成分可能结合在T淋巴细胞上。在结节病或恶性淋巴瘤患者中,通过结核菌素阳性供体的淋巴细胞被动转移结核菌素敏感性更为困难。在结节病中,只有使用比健康对照明显更多数量的供体淋巴细胞,才有可能在距转移部位相当远的地方出现阳性结核菌素反应。在恶性淋巴瘤患者中,这种转移很少成功。讨论了两组中迟发性免疫敏感性受损的定性和定量差异及其可能的原因。

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