Ron M A
Br J Psychiatry. 1986 Mar;148:235-46. doi: 10.1192/bjp.148.3.235.
The possibility that chronic abuse of volatile substances can cause permanent neurological, psychiatric, and intellectual sequelae is critically reviewed. Toluene, present in the commonly used adhesives, is most often implicated in 'glue sniffing'; this review focuses on its potential long-term effects. Many criticisms--particularly poor matching of control samples and inability to distinguish between acute and chronic effects--can be levelled at the available studies, while no adequate follow-up studies have been performed. In the light of present knowledge, the possibility that permanent structural brain damage, with accompanying psychiatric manifestations, results from solvent abuse remains inconclusive.
对长期滥用挥发性物质会导致永久性神经、精神和智力后遗症的可能性进行了批判性综述。常用粘合剂中含有的甲苯最常与“吸胶”有关；本综述重点关注其潜在的长期影响。现有研究存在许多可诟病之处——尤其是对照样本匹配不佳以及无法区分急性和慢性影响——而且尚未进行充分的随访研究。根据目前的知识，溶剂滥用是否会导致永久性脑结构损伤并伴有精神症状仍尚无定论。
