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儿童期进行杀锥虫治疗后血清学治愈相关的恰加斯心肌病

Chagas cardiomyopathy associated with serological cure after trypanocidal treatment during childhood.

作者信息

Fernández Marisa Liliana, Hernández Yolanda, Scollo Karenina, Esteva Mónica Ines, Riarte Adelina Rosa, Prado Nilda Graciela

机构信息

Departamento de Clínica, Patologia y Tratamiento, Instituto Nacional de Parasitología Dr. Mario Fatala Chaben, Ministerio de Salud, Buenos Aires, Argentina.

Departamento de Diagnostico, Instituto Nacional de Parasitología Dr. Mario Fatala Chaben, Ministerio de Salud, Buenos Aires, Argentina.

出版信息

Rev Soc Bras Med Trop. 2018 Jul-Aug;51(4):557-559. doi: 10.1590/0037-8682-0364-2017.

Abstract

Chagas disease is a chronic parasitological disease, which could cause cardiac manifestations in approximately one-third of affected individuals. Benznidazole and nifurtimox are used to treat this parasitological infection caused by Trypanosoma cruzi. Conventionally, the criterion for cure is consistently negative serological tests after treatment. We report a case of a patient who was treated when she was 13 years old and achieved T. cruzi negative seroconversion but developed Chagas disease cardiomyopathy as an adult.

摘要

恰加斯病是一种慢性寄生虫病,约三分之一的感染者会出现心脏症状。苯硝唑和硝呋莫司用于治疗由克氏锥虫引起的这种寄生虫感染。按照惯例,治愈的标准是治疗后血清学检测持续呈阴性。我们报告一例患者,其13岁时接受治疗,克氏锥虫血清学转换呈阴性,但成年后患上了恰加斯病心肌病。

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