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巴西麻风病高度流行市麻风病的流行病学和地理特征

Epidemiological and geographical characterization of leprosy in a Brazilian hyperendemic municipality.

作者信息

Marciano Lucia Helena Soares Camargo, Belone Andréa de Faria Fernandes, Rosa Patrícia Sammarco, Coelho Neusa Maria Broch, Ghidella Cássio César, Nardi Susilene Maria Tonelli, Miranda William Cabral, Barrozo Ligia Vizeu, Lastória Joel Carlos

机构信息

Instituto Lauro de Souza Lima, Bauru, Brasil.

Centro de Referência de Hanseníase e Tuberculose, Rondonópolis, Brasil.

出版信息

Cad Saude Publica. 2018 Aug 20;34(8):e00197216. doi: 10.1590/0102-311X00197216.

Abstract

This study aimed to identify the distribution pattern of leprosy in a hyperendemic municipality in Brazil and determine its relationship with the clinico-epidemiological situation over 11 years. The geographic information system, MapInfo, spatial scan statistics and the Moran I index were used to analyze new cases. The digital cartographic base was used to map clusters of new paucibacillary and multibacillary cases and cases in minors under 15 years old. Socioeconomic indicators are shown using the choropleth mapping technique. A reduction in the detection coefficient, increases in high-risk spatial clusters, marked changes in the distribution of high-risk and low-risk clusters, and high-risk clusters of minors under 15 years old were observed from 2006 to 2010, showing recent illness, the presence of active foci, and overlapping of high-risk clusters of multibacillary infection in minors under 15 years old. Leprosy remains a public health problem in Rondonópolis, Mato Grosso State; the high-risk areas require an intensification of control measures and active search strategies to detect new cases.

摘要

本研究旨在确定巴西一个麻风病高度流行市的麻风病分布模式,并确定其与11年临床流行病学情况的关系。利用地理信息系统MapInfo、空间扫描统计和莫兰I指数分析新病例。数字地图库用于绘制新的少菌型和多菌型病例以及15岁以下未成年人病例的聚集情况。社会经济指标采用分级统计图绘制技术展示。2006年至2010年期间,观察到检测系数降低、高风险空间聚集增加、高风险和低风险聚集分布的显著变化以及15岁以下未成年人的高风险聚集,表明近期发病、存在活跃病灶以及15岁以下未成年人多菌型感染的高风险聚集重叠。在马托格罗索州朗多诺波利斯,麻风病仍然是一个公共卫生问题;高风险地区需要加强控制措施和积极的搜索策略以发现新病例。

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