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[儿茶酚胺排泄作为神经根炎疼痛综合征患者治疗效果的指标]

[Catecholamine excretion as an index of the effectiveness of treatment in radiculitis patients with a pain syndrome].

作者信息

Gzelishvili M S, Shindian M A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(4):499-503.

PMID:301337
Abstract

The authors studied the excretion of catecholamines in the diurnal urine in patients with sacrolumbar and cervicothoracal radiculitis in the acute stage with pain and the changes of excretion under the influence of physiotherapy. In radiculities with the pain syndrome there was an activation of catecholamine systems, mainly in the hormonial link of the sympathico-adrenal system. Following treatment along with the disappearance of the pain syndrome there is a normalization of the excretion of adrenalin, noradrenalin and the terminal product of inactivated catecholamine in the diurnal urine. This gives ground to assume that the results of these biochemical studies may serve as indices of the therapeutic effectiveness.

摘要

作者研究了急性疼痛期腰骶部和颈胸部神经根炎患者日间尿中儿茶酚胺的排泄情况以及物理治疗影响下排泄的变化。在伴有疼痛综合征的神经根炎中,儿茶酚胺系统被激活,主要是在交感 - 肾上腺系统的激素环节。治疗后随着疼痛综合征的消失,日间尿中肾上腺素、去甲肾上腺素和失活儿茶酚胺终产物的排泄恢复正常。这使我们有理由认为这些生化研究结果可作为治疗效果的指标。

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