Department of Dermatology, University of Naples Federico II, Naples, Italy.
Int J Dermatol. 2018 Sep;57(9):1085-1087. doi: 10.1111/ijd.14128. Epub 2018 Jun 25.
Metastases from melanoma can be found in any organ, while the reported incidence of skin metastases varies between 2 and 20%. Cutaneous melanoma metastases (CMM) can be heterogeneous at clinical examination, and they can simulate other benign and malignant lesions, thus generating major diagnostic troubles for the dermatologist. Dermoscopy is a useful tool that may increase the physician's diagnostic accuracy to this purpose.
Herein, we describe the case of two patients having lesions that can easily be confused with other benign or malignant lesions for their clinical and dermoscopic similarities and for the variability of presentation of skin metastases. The description of the dermoscopy patterns of melanoma metastases may be useful to recognize early metastases, when clinically not suspected, facilitating an early removal and histopathological confirmation.
Diagnoses of melanoma metastases and angiomas were confirmed by histological examination. Melanoma metastases show at dermoscopic examination the angioma-like pattern. The ability to detect CMM between other lesions was good taking into consideration that, without the patient's history and with just the dermoscopy image, it could be very difficult to distinguish CMM from other benign or malignant skin lesions.
The present study confirms that dermoscopy is a useful tool to increase the physician's diagnostic accuracy for CMM and allow its differentiation from other cutaneous lesions, always taking into account the patient's medical record.
黑色素瘤转移可发生在任何器官,而皮肤转移的报告发生率在 2%至 20%之间。皮肤黑色素瘤转移(CMM)在临床检查时可能具有异质性,并且它们可以模拟其他良性和恶性病变,从而给皮肤科医生带来重大的诊断难题。皮肤镜检查是一种有用的工具,可以提高医生的诊断准确性。
在此,我们描述了两例患者的病例,这些病变的临床和皮肤镜下表现相似,且皮肤转移的表现也存在多样性,因此容易与其他良性或恶性病变混淆。描述黑色素瘤转移的皮肤镜模式可能有助于识别早期转移,当临床怀疑时,早期切除和组织病理学确认可以更早地进行。
通过组织学检查确诊为黑色素瘤转移和血管瘤。黑色素瘤转移在皮肤镜检查下显示出类似血管瘤的模式。考虑到没有患者的病史,仅凭皮肤镜图像,区分 CMM 与其他良性或恶性皮肤病变可能非常困难,因此,在考虑其他病变时,CMM 的检测能力良好。
本研究证实,皮肤镜检查是一种有用的工具,可以提高医生对 CMM 的诊断准确性,并允许其与其他皮肤病变区分开来,始终考虑患者的病历。