Sima A A, Ross R T, Hoag G, Rozdilsky B, Diocee M
Can J Neurol Sci. 1986 May;13(2):138-45. doi: 10.1017/s0317167100036088.
Two cases of malignant intracranial fibrous histiocytoma are presented. In Case 1 the tumour arose from the meninges and showed a disseminated spread throughout the neuroaxis. In the second case the tumour appeared to arise from within the brain substance. In this case surgical intervention and radiotherapy appeared to have achieved a cure, since no residual tumour was found at autopsy. The tumours were examined using ultrastructural and immunohistochemical techniques, which appeared advantageous in delineating this rare tumour from other intracranial neoplasms.
本文报告了两例恶性颅内纤维组织细胞瘤。病例1中,肿瘤起源于脑膜,呈弥漫性播散至整个神经轴。在第二例中,肿瘤似乎起源于脑实质内。在该病例中,手术干预和放疗似乎已实现治愈,因为尸检时未发现残留肿瘤。使用超微结构和免疫组化技术对肿瘤进行了检查,这些技术在将这种罕见肿瘤与其他颅内肿瘤区分开来方面似乎具有优势。