Mattsson W, Gynning I, Tropé C, Astedt B
Acta Radiol Ther Phys Biol. 1977 Apr;16(2):97-108. doi: 10.3109/02841867709134300.
Combination chemotherapy (vincristine, adriamycin, cyclophosphamide, methotrexate with leucoverin rescue) in 32 patients with metastatic carcinoma of the breast resulted in an overall response rate of 81 per cent (9/32 complete remission, 17/32 partial remission). No serious side effects were noted. Karnofsky performance index improved in 24/26 responders.
对32例转移性乳腺癌患者采用联合化疗（长春新碱、阿霉素、环磷酰胺、甲氨蝶呤加亚叶酸钙解救），总有效率为81%（9例完全缓解，17例部分缓解）。未观察到严重副作用。26例有效患者的卡氏功能状态评分有所改善。
