Carpel E F, Sigelman R J, Doughman D J
Am J Ophthalmol. 1977 May;83(5):629-32. doi: 10.1016/0002-9394(77)90127-1.
A family of ten individuals aged 18 months to 75 years had biomicroscopic findings consisting of large, amorphous, sheet-like opacifications of the posterior stroma and Descemet's membrane, and alterations of the endothelium. A uniform thinning of the cornea was present. These findings do not conform to previously described corneal dystrophies. The condition appears minimally progressive and the three-generation pedigree indicated an autosomal-dominant inheritance pattern.
一个由10名年龄在18个月至75岁之间的个体组成的家族,其生物显微镜检查结果包括后弹力层和Descemet膜的大片无定形片状混浊以及内皮改变。角膜存在均匀变薄。这些发现不符合先前描述的角膜营养不良。病情似乎进展极为缓慢,三代家系显示为常染色体显性遗传模式。