Chu Fangjia, Yan Sheng, Zheng Jiangen, Zhang Lingjun, Zhang Haiyan, Yu Keke, Sun Xiaonan, Liu Anping, Huang Yingzhou
Chongqing Key Laboratory of Soft Condensed Matter Physics and Smart Materials, College of Physics, Chongqing University, Chongqing, 400044, China.
Department of Applied Physics, College of Physics, Chongqing University, Chongqing, 400044, China.
Nanoscale Res Lett. 2018 Aug 22;13(1):244. doi: 10.1186/s11671-018-2658-3.
With high sensitivity at single molecule level, surface-enhanced Raman scattering (SERS) is considered as an ultrasensitive optical detection technology with broad application prospects in lots of fields. However, the complicated fabrication and unaffordable price of SERS substrate are still a roadblock on the way to be widely used in industry. In this work, the SERS spectra on a commercial laser engraved Teflon (PTFE) film with engraved microarray are investigated. The wettability of film surface modulated by laser engraving make the microarray have the ability to decrease the contact area on film surface while water evaporation. The SEM image of the engraved area points out the micro/nanostructures generated engraving process is crucial to its superhydrophobic property. The probing molecules (i.e., methylene blue and rhodamine6G) were utilized to investigate with the limit of detection (1 × 10 M). Furthermore, the biomolecule (bovine serum albumin) was used to demonstrate its benefits in biological applications. The measured intensities of Raman spectra on this PTFE with laser engraved microarray demonstrate its potential value for a SERS substrate. Our work on this simple, cheap SERS substrate with high sensitivity has a great commercial value and plenty of application in lots of fields.
表面增强拉曼散射（SERS）在单分子水平上具有高灵敏度，被认为是一种超灵敏的光学检测技术，在许多领域具有广阔的应用前景。然而，SERS基底复杂的制备工艺和高昂的价格仍然是其在工业中广泛应用的障碍。在这项工作中，我们研究了具有微阵列雕刻的商用激光雕刻聚四氟乙烯（PTFE）薄膜上的SERS光谱。激光雕刻调制的薄膜表面润湿性使微阵列在水蒸发时能够减小薄膜表面的接触面积。雕刻区域的扫描电子显微镜图像表明，雕刻过程中产生的微/纳米结构对其超疏水性能至关重要。利用探测分子（即亚甲基蓝和罗丹明6G）进行检测，检测限为1×10⁻⁹ M。此外，还使用生物分子（牛血清白蛋白）来证明其在生物应用中的优势。在这种具有激光雕刻微阵列的PTFE上测得的拉曼光谱强度证明了其作为SERS基底的潜在价值。我们对这种简单、廉价且具有高灵敏度的SERS基底的研究具有巨大的商业价值，并在许多领域有大量应用。
