Tunç Muzaffer, Şahutoğlu Cengiz, Karaca Nursen, Kocabaş Seden, Aşkar Fatma Zekiye
Department of Anaesthesiology and Reanimation, Ege University School of Medicine, İzmir, Turkey.
Turk J Anaesthesiol Reanim. 2018 Aug;46(4):283-291. doi: 10.5152/TJAR.2018.92244. Epub 2018 May 2.
Prolonged intensive care unit (ICU) stay prevents the use of ICU equipment by other patients and increases hospital cost. This retrospective study aimed to investigate the risk factors for prolonged ICU stay in patients undergoing open heart surgery.
The medical records of 513 patients who underwent coronary artery bypass grafting and valvular heart surgery were retrospectively evaluated. Patients were divided into two groups based on their ICU stay: groups I (<48 h) and II (≥48 h). The effect of patient variables on the ICU stay duration was investigated using logistic regression analysis.
The mean age of the patients was 61.5±10 years, and 69% were males. The ICU stay of ≥48 h was observed in 20.1% of the patients. Diabetes mellitus and low ejection fraction (pre-operative variables); long aortic cross clamp, cardiopulmonary bypass time and intra-aortic balloon pump requirement (intra-operative variables); arrhythmia, myocardial infarction, renal dysfunction and need for haemodialysis, use of ≥2 inotropic agents, infection, sepsis and respiratory complication (post-operative variables) were found to prolong the ICU stay. In multivariate logistic regression analysis, intra-aortic balloon pump requirement, use of ≥2 inotropic agents, post-operative myocardial infarction and need for haemodialysis were found to be independent risk factors for prolonged ICU stay (p<0.05). Early mortality was 0.97% (5 patients).
Intra-aortic balloon pump requirement, use of ≥2 inotropic agents, post-operative myocardial infarction and need for post-operative haemodialysis are independent risk factors for patients undergoing open heart surgery. Selection of methods for protecting the myocardium and renal functions during the intra-operative period would reduce the duration of ICU stay.
重症监护病房(ICU)长时间停留会妨碍其他患者使用ICU设备,并增加医院成本。本回顾性研究旨在调查接受心脏直视手术患者在ICU长时间停留的危险因素。
回顾性评估513例行冠状动脉搭桥术和心脏瓣膜手术患者的病历。根据患者在ICU的停留时间将其分为两组:I组(<48小时)和II组(≥48小时)。采用逻辑回归分析研究患者变量对ICU停留时间的影响。
患者的平均年龄为61.5±10岁,69%为男性。20.1%的患者在ICU停留时间≥48小时。发现糖尿病和低射血分数(术前变量);主动脉阻断时间长、体外循环时间和主动脉内球囊反搏需求(术中变量);心律失常、心肌梗死、肾功能不全和血液透析需求、使用≥2种血管活性药物、感染、脓毒症和呼吸并发症(术后变量)会延长ICU停留时间。在多因素逻辑回归分析中,主动脉内球囊反搏需求、使用≥2种血管活性药物、术后心肌梗死和血液透析需求被发现是ICU停留时间延长的独立危险因素(p<0.05)。早期死亡率为0.97%(5例患者)。
主动脉内球囊反搏需求、使用≥2种血管活性药物、术后心肌梗死和术后血液透析需求是接受心脏直视手术患者的独立危险因素。在手术期间选择保护心肌和肾功能的方法将缩短ICU停留时间。