Suppr超能文献

成人心脏直视手术后重症监护病房延长住院时间的危险因素

Risk Factors for Prolonged Intensive Care Unit Stay After Open Heart Surgery in Adults.

作者信息

Tunç Muzaffer, Şahutoğlu Cengiz, Karaca Nursen, Kocabaş Seden, Aşkar Fatma Zekiye

机构信息

Department of Anaesthesiology and Reanimation, Ege University School of Medicine, İzmir, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2018 Aug;46(4):283-291. doi: 10.5152/TJAR.2018.92244. Epub 2018 May 2.

Abstract

OBJECTIVE

Prolonged intensive care unit (ICU) stay prevents the use of ICU equipment by other patients and increases hospital cost. This retrospective study aimed to investigate the risk factors for prolonged ICU stay in patients undergoing open heart surgery.

METHODS

The medical records of 513 patients who underwent coronary artery bypass grafting and valvular heart surgery were retrospectively evaluated. Patients were divided into two groups based on their ICU stay: groups I (<48 h) and II (≥48 h). The effect of patient variables on the ICU stay duration was investigated using logistic regression analysis.

RESULTS

The mean age of the patients was 61.5±10 years, and 69% were males. The ICU stay of ≥48 h was observed in 20.1% of the patients. Diabetes mellitus and low ejection fraction (pre-operative variables); long aortic cross clamp, cardiopulmonary bypass time and intra-aortic balloon pump requirement (intra-operative variables); arrhythmia, myocardial infarction, renal dysfunction and need for haemodialysis, use of ≥2 inotropic agents, infection, sepsis and respiratory complication (post-operative variables) were found to prolong the ICU stay. In multivariate logistic regression analysis, intra-aortic balloon pump requirement, use of ≥2 inotropic agents, post-operative myocardial infarction and need for haemodialysis were found to be independent risk factors for prolonged ICU stay (p<0.05). Early mortality was 0.97% (5 patients).

CONCLUSION

Intra-aortic balloon pump requirement, use of ≥2 inotropic agents, post-operative myocardial infarction and need for post-operative haemodialysis are independent risk factors for patients undergoing open heart surgery. Selection of methods for protecting the myocardium and renal functions during the intra-operative period would reduce the duration of ICU stay.

摘要

目的

重症监护病房(ICU)长时间停留会妨碍其他患者使用ICU设备,并增加医院成本。本回顾性研究旨在调查接受心脏直视手术患者在ICU长时间停留的危险因素。

方法

回顾性评估513例行冠状动脉搭桥术和心脏瓣膜手术患者的病历。根据患者在ICU的停留时间将其分为两组:I组(<48小时)和II组(≥48小时)。采用逻辑回归分析研究患者变量对ICU停留时间的影响。

结果

患者的平均年龄为61.5±10岁,69%为男性。20.1%的患者在ICU停留时间≥48小时。发现糖尿病和低射血分数(术前变量);主动脉阻断时间长、体外循环时间和主动脉内球囊反搏需求(术中变量);心律失常、心肌梗死、肾功能不全和血液透析需求、使用≥2种血管活性药物、感染、脓毒症和呼吸并发症(术后变量)会延长ICU停留时间。在多因素逻辑回归分析中,主动脉内球囊反搏需求、使用≥2种血管活性药物、术后心肌梗死和血液透析需求被发现是ICU停留时间延长的独立危险因素(p<0.05)。早期死亡率为0.97%(5例患者)。

结论

主动脉内球囊反搏需求、使用≥2种血管活性药物、术后心肌梗死和术后血液透析需求是接受心脏直视手术患者的独立危险因素。在手术期间选择保护心肌和肾功能的方法将缩短ICU停留时间。

相似文献

引用本文的文献

7
Pharmacists in Critical Care.重症监护领域的药剂师。
Innov Pharm. 2019 Aug 31;10(1). doi: 10.24926/iip.v10i1.1640. eCollection 2019.

本文引用的文献

3
Factors influencing prolonged ICU stay after open heart surgery.心脏直视手术后影响重症监护病房(ICU)延长住院时间的因素。
Res Cardiovasc Med. 2014 Oct 14;3(4):e20159. doi: 10.5812/cardiovascmed.20159. eCollection 2014 Nov.
5
The role of gender in coronary surgery.性别在冠状动脉手术中的作用。
Eur J Cardiothorac Surg. 2011 Sep;40(3):715-21. doi: 10.1016/j.ejcts.2011.01.003. Epub 2011 Feb 23.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验